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Two adolescents with chronic adrenal insufficiency, presumably secondary to the cytomegalic type of congenital adrenal hypoplasia, developed a gonadotropin deficiency at puberty, which was both delayed and incomplete. Endocrine studies demonstrated in plasma low LH levels which failed to increase after LH-RH, higher levels of FSH, low basal testosterone concentration but increasing normally after HCG stimulation. Azoospermia was demonstrated in one case. In parallel with those previously reported, these two new cases show that the association between gonadotropin deficiency and congenital adrenal hypoplasia is not accidental, even if the relationship between the two components of the syndrome is still unclear.
J L Chaussain, and
M Roger, and
J C Job
January 1981,
Ceskoslovenska pediatrie,
J L Chaussain, and
M Roger, and
J C Job
May 1977,
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J L Chaussain, and
M Roger, and
J C Job
January 1971,
Verhandlungen der Deutschen Gesellschaft fur Pathologie,
J L Chaussain, and
M Roger, and
J C Job
June 1993,
American journal of medical genetics,
J L Chaussain, and
M Roger, and
J C Job
November 1981,
Horumon to rinsho. Clinical endocrinology,
J L Chaussain, and
M Roger, and
J C Job
June 1978,
Virchows Archiv. A, Pathological anatomy and histology,
J L Chaussain, and
M Roger, and
J C Job
February 1975,
Archives francaises de pediatrie,
J L Chaussain, and
M Roger, and
J C Job
January 1969,
Deutsche medizinische Wochenschrift (1946),
J L Chaussain, and
M Roger, and
J C Job
July 1974,
Ceskoslovenska gynekologie,
J L Chaussain, and
M Roger, and
J C Job
January 1976,
Annales d'endocrinologie,
