Biomaterial Database

Oral mannitol as a preparation for double contrast barium enema. 1982

K D Foord

A oral mannitol purgative which is used prior to colonoscopy proved disappointing for barium enema preparation. A number of ways of improving bowel clearance with mannitol in divided dosage, preliminary oral metoclopramide and a clear fluid diet have been assessed. Divided dosage and a clear fluid diet were both beneficial, whereas oral metoclopramide was ineffective. Using the best regime, 38% of patients had a totally clear bowel compared with 33% using an established lavage technique. It is concluded that oral mannitol, with a clear fluid diet, is a satisfactory preparation for double contrast barium enema, and a regime is recommended.

UI	MeSH Term	Description	Entries
D007507	Therapeutic Irrigation	The washing of a body cavity or surface by flowing water or solution for therapy or diagnosis.	Douching,Lavage,Douchings,Irrigation, Therapeutic,Irrigations, Therapeutic,Lavages,Therapeutic Irrigations
D008353	Mannitol	A diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity.	(L)-Mannitol,Osmitrol,Osmofundin
D008787	Metoclopramide	A dopamine D2 antagonist that is used as an antiemetic.	4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide,Cerucal,Maxolon,Metaclopramide,Metoclopramide Dihydrochloride,Metoclopramide Hydrochloride,Metoclopramide Monohydrochloride,Metoclopramide Monohydrochloride, Monohydrate,Primperan,Reglan,Rimetin,Dihydrochloride, Metoclopramide,Hydrochloride, Metoclopramide,Monohydrochloride, Metoclopramide
D002400	Cathartics	Agents that are used to stimulate evacuation of the bowels.	Bowel Evacuant,Bowel Preparation Solution,Cathartic,Purgative,Purgatives,Bowel Evacuants,Bowel Preparation Solutions,Evacuant, Bowel,Evacuants, Bowel,Preparation Solution, Bowel,Preparation Solutions, Bowel,Solution, Bowel Preparation,Solutions, Bowel Preparation
D004032	Diet	Regular course of eating and drinking adopted by a person or animal.	Diets
D004733	Enema	Insertion of a solution or compound through the RECTUM with the purpose of cleansing the COLON or for diagnostic procedures.	Enemata,Enemas,Enematas
D005769	Gastrointestinal Motility	The motor activity of the GASTROINTESTINAL TRACT.	Intestinal Motility,Gastrointestinal Motilities,Intestinal Motilities,Motilities, Gastrointestinal,Motilities, Intestinal,Motility, Gastrointestinal,Motility, Intestinal
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000284	Administration, Oral	The giving of drugs, chemicals, or other substances by mouth.	Drug Administration, Oral,Administration, Oral Drug,Oral Administration,Oral Drug Administration,Administrations, Oral,Administrations, Oral Drug,Drug Administrations, Oral,Oral Administrations,Oral Drug Administrations
D001466	Barium Sulfate	A compound used as an x-ray contrast medium that occurs in nature as the mineral barite. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield.	Barite,Baritop,Barium Sulfate (2:1),E-Z-CAT,Micropaque Oral,E Z CAT,EZCAT,Sulfate, Barium