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Unlike those experiments described in the previous several reports, a carcinogen was given to pregnant rats in our experiment to induce a tumor similar to yolk sac tumor which often occurs in human cases, aiming at contribution to establishment of an experimental model. Using Wister rat on the 10th day of gestation, ater removal of the fetus, the yolk sac was extracted out of the uterus, and a carcinogen was administered to it. Induced tumor was examined morphologically. By the 16th week after experiment, tumor was induced in 70% out of rats treated. The tumor volume was varied from a bean to a thumb tippize. Histologically, most of them were considered to be teratoma. But in 30% of them, human pure-type yolk sac tumor or the tumor similar to it were observed. Reticular and endodermal sinus or polyvesicular vitelline patterns were also clearly observed. Presence of hyaline body by PAS-staining and AFP by fluorescent antibody method were confirmed.
H Ito, and
T Sekine, and
T Tanaka, and
N Komuro, and
Y Hirakata, and
K Miyazaki, and
H Watanabe, and
T Hosokawa
January 1978,
Chirurgie pediatrique,
H Ito, and
T Sekine, and
T Tanaka, and
N Komuro, and
Y Hirakata, and
K Miyazaki, and
H Watanabe, and
T Hosokawa
January 1979,
[Hokkaido igaku zasshi] The Hokkaido journal of medical science,
H Ito, and
T Sekine, and
T Tanaka, and
N Komuro, and
Y Hirakata, and
K Miyazaki, and
H Watanabe, and
T Hosokawa
August 1976,
Nihon Hinyokika Gakkai zasshi. The japanese journal of urology,
H Ito, and
T Sekine, and
T Tanaka, and
N Komuro, and
Y Hirakata, and
K Miyazaki, and
H Watanabe, and
T Hosokawa
January 1981,
Nihon Sanka Fujinka Gakkai zasshi,
H Ito, and
T Sekine, and
T Tanaka, and
N Komuro, and
Y Hirakata, and
K Miyazaki, and
H Watanabe, and
T Hosokawa
May 1981,
[Hokkaido igaku zasshi] The Hokkaido journal of medical science,
H Ito, and
T Sekine, and
T Tanaka, and
N Komuro, and
Y Hirakata, and
K Miyazaki, and
H Watanabe, and
T Hosokawa
March 1988,
European journal of cancer & clinical oncology,
H Ito, and
T Sekine, and
T Tanaka, and
N Komuro, and
Y Hirakata, and
K Miyazaki, and
H Watanabe, and
T Hosokawa
October 1980,
Nihon Sanka Fujinka Gakkai zasshi,
H Ito, and
T Sekine, and
T Tanaka, and
N Komuro, and
Y Hirakata, and
K Miyazaki, and
H Watanabe, and
T Hosokawa
November 1979,
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine,
H Ito, and
T Sekine, and
T Tanaka, and
N Komuro, and
Y Hirakata, and
K Miyazaki, and
H Watanabe, and
T Hosokawa
April 1982,
RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin,
H Ito, and
T Sekine, and
T Tanaka, and
N Komuro, and
Y Hirakata, and
K Miyazaki, and
H Watanabe, and
T Hosokawa
January 1979,
Zhonghua fu chan ke za zhi,
