Biomaterial Database

[Effect of different doses of lysine on the free amino acid content of the blood serum]. 1982

V Vrubcheva, and N Ibrishimov

Investigations were carried out of the effect of various doses of lysine in the feed (6, 12, 24, and 30 g per fodder unit) on the amount of the total proteins, hemoglobin, and free amino acids in the blood serum. It was found that the free amino acids in the blood serum of sheep directly correlated with the content of lysine in the diet. The addition of 6 g lysine per fodder unit supplied the most adequate amount of amino acids in the body to meet the metabolic requirements. The concentration of free lysine in the serum remained at a comparatively/relatively constant level (2.5 mg%), the amount of total protein and hemoglobin was highest (within the range of the physiologic norms), and the general status of the animals proved best. The higher rates of lysine (24 and 30 g per fodder unit) led to an abrupt change in the concentration of all free amino acids in the serum, most strongly being affected glycine, aspartic acid, glutamic acid, alanine, and leucin. The amount of free amino acids (lysine) in the blood serum rose parallel to the increase in the lysine doses in the ration of sheep. At 30 g lysine per fodder unit there was a fivefold rise as against the control group.

UI	MeSH Term	Description	Entries
D008239	Lysine	An essential amino acid. It is often added to animal feed.	Enisyl,L-Lysine,Lysine Acetate,Lysine Hydrochloride,Acetate, Lysine,L Lysine
D004305	Dose-Response Relationship, Drug	The relationship between the dose of an administered drug and the response of the organism to the drug.	Dose Response Relationship, Drug,Dose-Response Relationships, Drug,Drug Dose-Response Relationship,Drug Dose-Response Relationships,Relationship, Drug Dose-Response,Relationships, Drug Dose-Response
D005260	Female		Females
D005609	Free Radicals	Highly reactive molecules with an unsatisfied electron valence pair. Free radicals are produced in both normal and pathological processes. Free radicals include reactive oxygen and nitrogen species (RONS). They are proven or suspected agents of tissue damage in a wide variety of circumstances including radiation, damage from environment chemicals, and aging. Natural and pharmacological prevention of free radical damage is being actively investigated.	Free Radical
D000596	Amino Acids	Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins.	Amino Acid,Acid, Amino,Acids, Amino
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D012756	Sheep	Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.	Ovis,Sheep, Dall,Dall Sheep,Ovis dalli
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor