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Rat pups were treated on postnatal day 5 either with the combination of desmethylimipramine (DMI) and 6-hydroxydopamine (6-OHDA) to produce depletion of brain dopamine, or with control injections of saline. Two days later they were presented a novel anise odor paired with intraoral baby formula, and on the next day were tested for preference for the novel odor. Before conditioning and testing, animals were treated with either apomorphine (0.05 mg/kg) or isotonic saline. Performance of the conditioned appetitive response was impaired in dopamine depleted animals. In DMI/6-OHDA treated pups, apomorphine administration prior to conditioning produced an improvement in performance, but drug treatment prior to testing had no effect. In normal pups, apomorphine administration either before conditioning or testing produced impaired performance at testing.
D A Weldon, and
R S Wool, and
M H Teicher, and
B A Shaywitz, and
D J Cohen, and
G M Anderson
September 1980,
Pharmacology, biochemistry, and behavior,
D A Weldon, and
R S Wool, and
M H Teicher, and
B A Shaywitz, and
D J Cohen, and
G M Anderson
July 1978,
Archives of neurology,
D A Weldon, and
R S Wool, and
M H Teicher, and
B A Shaywitz, and
D J Cohen, and
G M Anderson
January 1979,
Physiology & behavior,
D A Weldon, and
R S Wool, and
M H Teicher, and
B A Shaywitz, and
D J Cohen, and
G M Anderson
August 1978,
Pharmacology, biochemistry, and behavior,
D A Weldon, and
R S Wool, and
M H Teicher, and
B A Shaywitz, and
D J Cohen, and
G M Anderson
September 1981,
Pharmacology, biochemistry, and behavior,
D A Weldon, and
R S Wool, and
M H Teicher, and
B A Shaywitz, and
D J Cohen, and
G M Anderson
January 1984,
Psychopharmacology,
D A Weldon, and
R S Wool, and
M H Teicher, and
B A Shaywitz, and
D J Cohen, and
G M Anderson
July 1982,
Developmental psychobiology,
D A Weldon, and
R S Wool, and
M H Teicher, and
B A Shaywitz, and
D J Cohen, and
G M Anderson
June 1990,
Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology,
D A Weldon, and
R S Wool, and
M H Teicher, and
B A Shaywitz, and
D J Cohen, and
G M Anderson
July 1972,
European journal of pharmacology,
D A Weldon, and
R S Wool, and
M H Teicher, and
B A Shaywitz, and
D J Cohen, and
G M Anderson
January 1979,
Neurobehavioral toxicology,
