Biomaterial Database

Zinc, nitrogen, copper, iron, and manganese balance in adolescent females fed two levels of zinc. 1978

J L Greger, and S C Zaikis, and R P Abernathy, and O A Bennett, and J Huffman

The effect of feeding two different levels of zinc (Diet Z11.5 and Diet Z14.7) on zinc, nitrogen, copper, iron, and manganese balances was determined in 11 girls, 12.5 to 14.2 years, during a 30-day period. Diet Z11.5 provided 11.32 or 11.64 mg zinc daily, levels similar to that determined previously to be consumed by average adolescent females. Diet Z14.7 provided 14.52 or 14.84 mg zinc daily. These levels were just slightly less than the Recommended Dietary Allowance for zinc. When fed Diet Z14.7, subjects lost significantly more zinc in their feces than when fed Diet Z11.5. Regression analyses were applied to the zinc balance data from this study and a previous study with adolescent females. By extrapolation, a dietary intake of 11 mg zinc daily was estimated to compensate for fecal and urinary zinc losses of the average girl in these studies. The standard error of the estimate was 2.18 mg zinc daily. Nitrogen excretion and retention were unaffected by the variations in zinc intake. Copper excretion in the feces was significantly increased when subjects were fed Diet Z14.7 rather than Diet Z11.5. Manganese and iron fecal losses were also significantly correlated to zinc fecal losses.

UI	MeSH Term	Description	Entries
D007501	Iron	A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.	Iron-56,Iron 56
D008345	Manganese	A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
D009584	Nitrogen	An element with the atomic symbol N, atomic number 7, and atomic weight [14.00643; 14.00728]. Nitrogen exists as a diatomic gas and makes up about 78% of the earth's atmosphere by volume. It is a constituent of proteins and nucleic acids and found in all living cells.
D009751	Nutritional Requirements	The amounts of various substances in food needed by an organism to sustain healthy life.	Dietary Requirements,Nutrition Requirements,Dietary Requirement,Nutrition Requirement,Nutritional Requirement,Requirement, Dietary,Requirement, Nutrition,Requirement, Nutritional,Requirements, Dietary,Requirements, Nutrition,Requirements, Nutritional
D003300	Copper	A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.	Copper-63,Copper 63
D004032	Diet	Regular course of eating and drinking adopted by a person or animal.	Diets
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D015032	Zinc	A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.