-transparent.png){kind=logo}
Hyperuricaemia was encountered in 29% of 55 subjects with essential hypertension, who had not been treated with anti-hypertensive drugs, as against a 10% incidence in a group with normal blood pressure. No relationship between hyperuricaemia and level of hypertension was found. The normal glomerular filtration, the frequent reduction in uric acid clearance and its correlation with uricaemia are held to be indicative of a tubular defect in the excretion of uric acid, as a cause of hyperuricaemia. The reduction in renal plasma flow and its significant correlation with uricaemia and uric acid clearance are considered probable causes of reduced renal excretion. In conclusion it is hypothesised that hypertension triggers renal haemodynamic disturbances and hence hyperuricaemia.
G Guerrera, and
D Melina, and
F Cocco
January 1964,
Lyon chirurgical,
G Guerrera, and
D Melina, and
F Cocco
May 1985,
Recenti progressi in medicina,
G Guerrera, and
D Melina, and
F Cocco
October 1980,
Klinische Wochenschrift,
G Guerrera, and
D Melina, and
F Cocco
December 1985,
Zhonghua nei ke za zhi,
G Guerrera, and
D Melina, and
F Cocco
June 2007,
Hypertension (Dallas, Tex. : 1979),
G Guerrera, and
D Melina, and
F Cocco
November 1977,
Metabolism: clinical and experimental,
G Guerrera, and
D Melina, and
F Cocco
January 1951,
Marseille chirurgical,
G Guerrera, and
D Melina, and
F Cocco
February 1965,
Hispalis medica; revista sevillana de medicina y cirugia,
G Guerrera, and
D Melina, and
F Cocco
January 1975,
Przeglad lekarski,
G Guerrera, and
D Melina, and
F Cocco
October 1988,
East African medical journal,
