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Vacuolization of the polymorphonuclear leukocyte (PMN) has generally been regarded as an indication of bacterial infection and has been particularly useful in diagnosing septicemia. In an effort to predict septicemia, peripheral blood smears from 69 febrile children were examined and systematically scored for severity of vacuolization. Thirteen children had remarkable vacuolization compared to the others. These 13 included only five children with bacterial illnesses and only one of the seven children with septicemia. Our finding that PMN vacuolization was neither diagnostic of septicemia nor predictive of bacterial infection suggests that the specificity of the link between vacuoles and bacteremia needs to be reassessed.
R C Adams, and
J H Dixon, and
E R Eichner
March 1978,
Indian pediatrics,
R C Adams, and
J H Dixon, and
E R Eichner
March 1995,
Clinical and diagnostic laboratory immunology,
R C Adams, and
J H Dixon, and
E R Eichner
July 1989,
Journal of chemotherapy (Florence, Italy),
R C Adams, and
J H Dixon, and
E R Eichner
October 2002,
International immunopharmacology,
R C Adams, and
J H Dixon, and
E R Eichner
October 1991,
The British journal of surgery,
R C Adams, and
J H Dixon, and
E R Eichner
October 1966,
Archives of internal medicine,
R C Adams, and
J H Dixon, and
E R Eichner
November 2017,
The Journal of pediatrics,
R C Adams, and
J H Dixon, and
E R Eichner
January 1979,
The Journal of pediatrics,
R C Adams, and
J H Dixon, and
E R Eichner
December 1977,
American journal of clinical pathology,
R C Adams, and
J H Dixon, and
E R Eichner
January 1995,
Methods in molecular biology (Clifton, N.J.),
