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The terms dry eye and keratoconjunctivitis sicca (KCS) imply a condition of highly reduced or absent tear film that often is not clinically demonstrable despite the presence of other signs and symptoms. In 52 patients with KCS symptoms, either with or without tear volume reduction as measured by Schirmer's basic secretion test, we found a statistically significant increase in water evaporation rate from the tear film when compared with normal subjects. Such an increased evaporation rate might account for the tear hypertonicity known to be associated with KCS and postulated to be responsible for ocular surface damage. Thus, we propose to identify this group of paradoxically wet "dry eyes" as a "syndrome of increased tear evaporation", which better describes the pathogenesis of the ocular condition.
M Rolando, and
M F Refojo, and
K R Kenyon
January 1974,
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M Rolando, and
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K R Kenyon
April 1989,
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M Rolando, and
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M Rolando, and
M F Refojo, and
K R Kenyon
April 1978,
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M Rolando, and
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K R Kenyon
June 2016,
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M Rolando, and
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K R Kenyon
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M Rolando, and
M F Refojo, and
K R Kenyon
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M Rolando, and
M F Refojo, and
K R Kenyon
February 2018,
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M Rolando, and
M F Refojo, and
K R Kenyon
January 2017,
Open veterinary journal,
M Rolando, and
M F Refojo, and
K R Kenyon
June 2023,
Translational vision science & technology,
