[Morphological abnormalities of nailbed capillaries in connective tissue diseases]. 1983

P Priollet, and M Vayssairat, and E Housset

The Capillaroscopy Unit of Broussais Hospital has carried out more than 6,000 examinations involving all areas of pathology and more particularly the special role which the method plays in connective tissue diseases. This experience was used to attempt to define the characteristics of the morphological abnormalities of the nailbed capillaries in connective tissue diseases in the adult. The study was deliberately limited to abnormalities of the capillaries themselves, with the exclusion of abnormalities of the pericapillary spaces, abnormalities of blood flow and abnormalities capable of manifesting themselves in the cold; though bearing in mind that the interpretation of a capillaroscopic examination can be perfectly credible only if all such anomalies are taken into consideration. The following capillaroscopic appearances have been included under the heading "morphological abnormalities": dystrophies, dilatations of the loops without megacapillaries, megacapillaries, telangiectasia, filiform loops, regressive capillaries, long loops and microaneurysms. Groups of these morphological abnormalities form more or less typical associations in connective tissue diseases.

UI MeSH Term Description Entries
D009262 Nails The thin, horny plates that cover the dorsal surfaces of the distal phalanges of the fingers and toes of primates. Fingernails,Toenails,Fingernail,Nail,Toenail
D002196 Capillaries The minute vessels that connect arterioles and venules. Capillary Beds,Sinusoidal Beds,Sinusoids,Bed, Sinusoidal,Beds, Sinusoidal,Capillary,Capillary Bed,Sinusoid,Sinusoidal Bed
D003240 Connective Tissue Diseases A heterogeneous group of disorders, some hereditary, others acquired, characterized by abnormal structure or function of one or more of the elements of connective tissue, i.e., collagen, elastin, or the mucopolysaccharides. Connective Tissue Disease,Disease, Connective Tissue,Diseases, Connective Tissue
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D012595 Scleroderma, Systemic A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA. Sclerosis, Systemic,Systemic Scleroderma,Systemic Sclerosis

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