Biomaterial Database

Blood and liver concentrations of glutathione, and plasma concentrations of sulfur-containing amino acids in chicks fed deficient, adequate, or excess levels of dietary cysteine. 1983

K P Boebel, and D H Baker

Experiments were conducted with young male chicks to examine the influence of cysteine status on blood and liver glutathione (GSH) concentrations and plasma sulfur amino acids. The equivalence of cystine, cysteine, and GSH as sources of dietary cysteine for the chick was reconfirmed. Whole-blood GSH was unresponsive to dietary cysteine level, but liver GSH increased as dietary cysteine increased from a deficient level to the required level. Excess levels of cysteine (two or four times the chick's requirement) elicited no further increase in hepatic GSH. Plasma cystine concentration increased markedly (i.e., ninefold) and in a linear fashion while plasma cysteine increased only modestly (i.e., twofold) as dietary cysteine level increased.

UI	MeSH Term	Description	Entries
D008099	Liver	A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances.	Livers
D002645	Chickens	Common name for the species Gallus gallus, the domestic fowl, in the family Phasianidae, order GALLIFORMES. It is descended from the red jungle fowl of SOUTHEAST ASIA.	Gallus gallus,Gallus domesticus,Gallus gallus domesticus,Chicken
D003545	Cysteine	A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.	Cysteine Hydrochloride,Half-Cystine,L-Cysteine,Zinc Cysteinate,Half Cystine,L Cysteine
D004032	Diet	Regular course of eating and drinking adopted by a person or animal.	Diets
D005978	Glutathione	A tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.	Reduced Glutathione,gamma-L-Glu-L-Cys-Gly,gamma-L-Glutamyl-L-Cysteinylglycine,Glutathione, Reduced,gamma L Glu L Cys Gly,gamma L Glutamyl L Cysteinylglycine
D000603	Amino Acids, Sulfur		Sulfur Amino Acid,Sulfur Amino Acids,Acid, Sulfur Amino,Acids, Sulfur Amino,Amino Acid, Sulfur
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia