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24 patients admitted to hospital between December 1, 1977 and March 3, 1978 with cultural or serological evidence of influenza A infection were retrospectively analyzed for evidence of elevated creatine phosphokinase (CPK) levels. 14 patients had elevated CPK levels not attributable to usual causes. Muscle biopsies from 2 patients showed focal necrosis and myopathic changes. Influenza A/Texas/1/77 was isolated from the biopsy specimen of 1 patient. Patients with elevated CPK levels tended to have greater per day hospital costs and more complications than patients with normal CPK levels. Elevated CPK levels are relatively common in hospitalized patients with influenza and may be due to influenza virus involvement of skeletal muscle.
H A Kessler, and
G M Trenholme, and
N J Vogelzang, and
R Patterson, and
J D Semel, and
A A Harris, and
S Levin
June 2009,
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists,
H A Kessler, and
G M Trenholme, and
N J Vogelzang, and
R Patterson, and
J D Semel, and
A A Harris, and
S Levin
October 1986,
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H A Kessler, and
G M Trenholme, and
N J Vogelzang, and
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A A Harris, and
S Levin
March 1984,
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H A Kessler, and
G M Trenholme, and
N J Vogelzang, and
R Patterson, and
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A A Harris, and
S Levin
February 1982,
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H A Kessler, and
G M Trenholme, and
N J Vogelzang, and
R Patterson, and
J D Semel, and
A A Harris, and
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January 1993,
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H A Kessler, and
G M Trenholme, and
N J Vogelzang, and
R Patterson, and
J D Semel, and
A A Harris, and
S Levin
September 1971,
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H A Kessler, and
G M Trenholme, and
N J Vogelzang, and
R Patterson, and
J D Semel, and
A A Harris, and
S Levin
February 1985,
The American review of respiratory disease,
H A Kessler, and
G M Trenholme, and
N J Vogelzang, and
R Patterson, and
J D Semel, and
A A Harris, and
S Levin
March 1991,
The Keio journal of medicine,
H A Kessler, and
G M Trenholme, and
N J Vogelzang, and
R Patterson, and
J D Semel, and
A A Harris, and
S Levin
September 2003,
Internal medicine (Tokyo, Japan),
H A Kessler, and
G M Trenholme, and
N J Vogelzang, and
R Patterson, and
J D Semel, and
A A Harris, and
S Levin
July 1983,
Archives of surgery (Chicago, Ill. : 1960),
