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Adrenal androgen levels and excretion increase during adrenarche and puberty. During this time the width of the adrenal zona reticularis has been reported to increase, and this fact is quoted as evidence for the common assumption that the major source of adrenal androgens is the zona reticularis. During human aging there is a marked decrease in adrenal androgen levels and excretion. In the present study, the width of the zona reticularis was studied single blind in multiple sections of the adrenals of 42 victims of sudden death 4 months to 93 years of age to discern a possible correlation between zona reticularis width and the declining adrenal androgen levels and excretion typical of aging. However, no correlation was found, which suggests that direct measurements of adrenal steroid secretion by the individual adrenal zones are necessary for the study of adrenal zonation.
L N Parker, and
E T Lifrak, and
M B Ramadan, and
M K Lai
January 1959,
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L N Parker, and
E T Lifrak, and
M B Ramadan, and
M K Lai
May 2021,
Molecular and cellular endocrinology,
L N Parker, and
E T Lifrak, and
M B Ramadan, and
M K Lai
March 2014,
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L N Parker, and
E T Lifrak, and
M B Ramadan, and
M K Lai
December 2020,
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L N Parker, and
E T Lifrak, and
M B Ramadan, and
M K Lai
November 2004,
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L N Parker, and
E T Lifrak, and
M B Ramadan, and
M K Lai
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L N Parker, and
E T Lifrak, and
M B Ramadan, and
M K Lai
April 1990,
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L N Parker, and
E T Lifrak, and
M B Ramadan, and
M K Lai
November 2007,
Annals of the New York Academy of Sciences,
L N Parker, and
E T Lifrak, and
M B Ramadan, and
M K Lai
February 2001,
Molecular and cellular endocrinology,
L N Parker, and
E T Lifrak, and
M B Ramadan, and
M K Lai
December 2022,
International journal of molecular sciences,
