BIOMAT Database Logo BIOMAT Database Logo

[Relationship between androgen and estrogen receptors and clinico-morphological characteristics of prostatic cancer]. 1983

L S Bassalyk, and A S Petrova, and V D Ermilova, and V K Sokolova, and N E Kushlinskiĭ

The paper presents the results of studies on cytoplasmic receptors of androgens (AR) and estrogens (ER) in tumors of 50 patients with prostate carcinoma with respect to age, histological structure and degree of tumor differentiation, and stage of the disease. The study showed the majority of tumors in patients not previously treated with estrogens to contain one or both types of receptors. In prostate carcinoma AR were found more frequently and both receptors were present twice as frequently in elderly as compared to senile patients. In the latter, adenocarcinomas containing only ER were predominant. AR could be detected more frequently in highly differentiated than in poorly differentiated tumors. ER did not correlate with the histological structure and degree of differentiation of the tumor. A negative correlation was observed between the stage of the tumor progression and the presence of AR in prostate carcinoma. AR and ER were seldom found in tumors of the patients treated with estrogens for a long time. Among 13 patients who died from advanced tumor, no AR were found in 12 tumors, both receptors were present in 1 tumor, and ER alone in 5 tumors.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011379 Prognosis A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations. Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D011471 Prostatic Neoplasms Tumors or cancer of the PROSTATE. Cancer of Prostate,Prostate Cancer,Cancer of the Prostate,Neoplasms, Prostate,Neoplasms, Prostatic,Prostate Neoplasms,Prostatic Cancer,Cancer, Prostate,Cancer, Prostatic,Cancers, Prostate,Cancers, Prostatic,Neoplasm, Prostate,Neoplasm, Prostatic,Prostate Cancers,Prostate Neoplasm,Prostatic Cancers,Prostatic Neoplasm
D011944 Receptors, Androgen Proteins, generally found in the CYTOPLASM, that specifically bind ANDROGENS and mediate their cellular actions. The complex of the androgen and receptor migrates to the CELL NUCLEUS where it induces transcription of specific segments of DNA. Androgen Receptors,5 alpha-Dihydrotestosterone Receptor,Androgen Receptor,Dihydrotestosterone Receptors,Receptor, Testosterone,Receptors, Androgens,Receptors, Dihydrotestosterone,Receptors, Stanolone,Stanolone Receptor,Testosterone Receptor,5 alpha Dihydrotestosterone Receptor,Androgens Receptors,Receptor, 5 alpha-Dihydrotestosterone,Receptor, Androgen,Receptor, Stanolone,Stanolone Receptors,alpha-Dihydrotestosterone Receptor, 5
D011960 Receptors, Estrogen Cytoplasmic proteins that bind estrogens and migrate to the nucleus where they regulate DNA transcription. Evaluation of the state of estrogen receptors in breast cancer patients has become clinically important. Estrogen Receptor,Estrogen Receptors,Estrogen Nuclear Receptor,Estrogen Receptor Type I,Estrogen Receptor Type II,Estrogen Receptors Type I,Estrogen Receptors Type II,Receptor, Estrogen Nuclear,Receptors, Estrogen, Type I,Receptors, Estrogen, Type II,Nuclear Receptor, Estrogen,Receptor, Estrogen
D011987 Receptors, Steroid Proteins found usually in the cytoplasm or nucleus that specifically bind steroid hormones and trigger changes influencing the behavior of cells. The steroid receptor-steroid hormone complex regulates the transcription of specific genes. Corticosteroid Receptors,Receptors, Corticosteroid,Steroid Receptors,Corticosteroid Receptor,Receptors, Steroids,Steroid Receptor,Receptor, Corticosteroid,Receptor, Steroid,Steroids Receptors
D004967 Estrogens Compounds that interact with ESTROGEN RECEPTORS in target tissues to bring about the effects similar to those of ESTRADIOL. Estrogens stimulate the female reproductive organs, and the development of secondary female SEX CHARACTERISTICS. Estrogenic chemicals include natural, synthetic, steroidal, or non-steroidal compounds. Estrogen,Estrogen Effect,Estrogen Effects,Estrogen Receptor Agonists,Estrogenic Agents,Estrogenic Compounds,Estrogenic Effect,Estrogenic Effects,Agents, Estrogenic,Agonists, Estrogen Receptor,Compounds, Estrogenic,Effects, Estrogen,Effects, Estrogenic,Receptor Agonists, Estrogen
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000230 Adenocarcinoma A malignant epithelial tumor with a glandular organization. Adenocarcinoma, Basal Cell,Adenocarcinoma, Granular Cell,Adenocarcinoma, Oxyphilic,Adenocarcinoma, Tubular,Adenoma, Malignant,Carcinoma, Cribriform,Carcinoma, Granular Cell,Carcinoma, Tubular,Adenocarcinomas,Adenocarcinomas, Basal Cell,Adenocarcinomas, Granular Cell,Adenocarcinomas, Oxyphilic,Adenocarcinomas, Tubular,Adenomas, Malignant,Basal Cell Adenocarcinoma,Basal Cell Adenocarcinomas,Carcinomas, Cribriform,Carcinomas, Granular Cell,Carcinomas, Tubular,Cribriform Carcinoma,Cribriform Carcinomas,Granular Cell Adenocarcinoma,Granular Cell Adenocarcinomas,Granular Cell Carcinoma,Granular Cell Carcinomas,Malignant Adenoma,Malignant Adenomas,Oxyphilic Adenocarcinoma,Oxyphilic Adenocarcinomas,Tubular Adenocarcinoma,Tubular Adenocarcinomas,Tubular Carcinoma,Tubular Carcinomas

Related Publications

L S Bassalyk, and A S Petrova, and V D Ermilova, and V K Sokolova, and N E Kushlinskiĭ
[Clinico-morphological characteristics of latent form of prostatic cancer].
May 1979, Vestnik khirurgii imeni I. I. Grekova,
L S Bassalyk, and A S Petrova, and V D Ermilova, and V K Sokolova, and N E Kushlinskiĭ
[Relation between estrogen receptors and the clinical morphological characteristics of primary breast cancer].
January 1981, Arkhiv patologii,
L S Bassalyk, and A S Petrova, and V D Ermilova, and V K Sokolova, and N E Kushlinskiĭ
Androgen and estrogen receptors in the cytosol from male rat anterior hypophysis: further characteristics and differentiation between androgen and estrogen receptors.
October 1976, Journal of steroid biochemistry,
L S Bassalyk, and A S Petrova, and V D Ermilova, and V K Sokolova, and N E Kushlinskiĭ
Immunolocalization of androgen receptors, estrogen alpha receptors, and estrogen beta receptors in experimentally induced canine prostatic hyperplasia.
January 2009, Journal of andrology,
L S Bassalyk, and A S Petrova, and V D Ermilova, and V K Sokolova, and N E Kushlinskiĭ
[Clinico-morphological characteristics of gallbladder cancer].
January 1990, Klinicheskaia khirurgiia,
L S Bassalyk, and A S Petrova, and V D Ermilova, and V K Sokolova, and N E Kushlinskiĭ
Androgen, estrogen and progesterone receptors of the R3327H Copenhagen rat prostatic tumor.
January 1979, Cancer letters,
L S Bassalyk, and A S Petrova, and V D Ermilova, and V K Sokolova, and N E Kushlinskiĭ
Differential expression of androgen, estrogen, and progesterone receptors in benign prostatic hyperplasia.
July 2016, Bosnian journal of basic medical sciences,
L S Bassalyk, and A S Petrova, and V D Ermilova, and V K Sokolova, and N E Kushlinskiĭ
Relationship between prostatic cytoplasmic and nuclear androgen receptors in patients with carcinoma of the prostate.
January 1981, European urology,
L S Bassalyk, and A S Petrova, and V D Ermilova, and V K Sokolova, and N E Kushlinskiĭ
[Clinico-morphological characteristics of bilateral breast cancer].
January 1978, Arkhiv patologii,
L S Bassalyk, and A S Petrova, and V D Ermilova, and V K Sokolova, and N E Kushlinskiĭ
Relationship between proliferative activity and estrogen receptors in breast cancer.
August 1979, Cancer,
Copied contents to your clipboard!