Biomaterial Database

[Relationship between dose rate and oxygen effect (author's transl)]. 1978

R Born

Chinese hamster cells were exposed to 60Co gamma-rays using dose rates between 3.64 and 0,01 Gy/min under euoxic or chronically hypoxic conditions of growth in order to clarify the relationship of the oxygen enhancement ratio (OER) to the dose rate. It turned out that the D0 of dose-effect curves from cells irradiated under euoxic conditions was increasing from 1.35 to 4.5 Gy with decreasing dose rates, whereas the curves from cells irradiated under chronically hypoxic conditions were not much influenced by the dose rate. The oxygen enhancement ratio decreased from 3.9 with 1.35 Gy/min to 1.8 with 0.07 Gy/min.

UI	MeSH Term	Description	Entries
D011829	Radiation Dosage	The amount of radiation energy that is deposited in a unit mass of material, such as tissues of plants or animal. In RADIOTHERAPY, radiation dosage is expressed in gray units (Gy). In RADIOLOGIC HEALTH, the dosage is expressed by the product of absorbed dose (Gy) and quality factor (a function of linear energy transfer), and is called radiation dose equivalent in sievert units (Sv).	Sievert Units,Dosage, Radiation,Gray Units,Gy Radiation,Sv Radiation Dose Equivalent,Dosages, Radiation,Radiation Dosages,Units, Gray,Units, Sievert
D011867	Radioisotope Teletherapy	A type of high-energy radiotherapy using a beam of gamma-radiation produced by a radioisotope source encapsulated within a teletherapy unit.	Teleradioisotope Therapy,Teletherapy, Radioisotope,Therapy, Teleradioisotope
D003037	Cobalt Radioisotopes	Unstable isotopes of cobalt that decay or disintegrate emitting radiation. Co atoms with atomic weights of 54-64, except 59, are radioactive cobalt isotopes.	Radioisotopes, Cobalt
D006224	Cricetinae	A subfamily in the family MURIDAE, comprising the hamsters. Four of the more common genera are Cricetus, CRICETULUS; MESOCRICETUS; and PHODOPUS.	Cricetus,Hamsters,Hamster
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D000860	Hypoxia	Sub-optimal OXYGEN levels in the ambient air of living organisms.	Anoxia,Oxygen Deficiency,Anoxemia,Deficiency, Oxygen,Hypoxemia,Deficiencies, Oxygen,Oxygen Deficiencies