Biomaterial Database

[Indirect lymphography of the urinary bladder in animal experiments (author's transl)]. 1978

R Harzmann, and R Chiari, and G Dhom, and F H Lehnhardt

Of three contrast media injected interdigitally and submucosally as well as instilled into the bladder, Lipiodol UF (particle size of over 15 micron) and the experimental compound AG 52-315 were not resorbed. Another experimental compound (AG 60-99) with an iodine content of 20% and a particle size of ca. 3,5 micron produced, when injected interdigitally, good contrast of the popliteal lymph nodes in all cases (n = 5). Instillation of the same contrast medium into the bladders of five dogs yielded subdued contrast of the paravesicular lymph nodes in one case. Of still another five animals, two showed contrast of the inner iliac lymph nodes after submucosal infiltration of the bladder mucosa with AG 60-99. In all cases (n = 15) inflammatory reaction with necrotic formations were observed. Resorption of the contrast medium was accomplished by heating at 39 degrees C, and was not improved by addition of Hyaluronidase. Because of the low local tolerance of the contrast medium preparation, this successful experiment in indirect lymphography of the urinary bladder of animals cannot be applied clinically.

UI	MeSH Term	Description	Entries
D008220	Lymphography	Radiographic study of the lymphatic system following injection of dye or contrast medium.	Lymphangiography,Lymphangiographies,Lymphographies
D009336	Necrosis	The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
D011877	Radionuclide Imaging	The production of an image obtained by cameras that detect the radioactive emissions of an injected radionuclide as it has distributed differentially throughout tissues in the body. The image obtained from a moving detector is called a scan, while the image obtained from a stationary camera device is called a scintiphotograph.	Gamma Camera Imaging,Radioisotope Scanning,Scanning, Radioisotope,Scintigraphy,Scintiphotography,Imaging, Gamma Camera,Imaging, Radionuclide
D001743	Urinary Bladder	A musculomembranous sac along the URINARY TRACT. URINE flows from the KIDNEYS into the bladder via the ureters (URETER), and is held there until URINATION.	Bladder,Bladder Detrusor Muscle,Detrusor Urinae,Bladder Detrusor Muscles,Bladder, Urinary,Detrusor Muscle, Bladder,Detrusor Muscles, Bladder
D003287	Contrast Media	Substances used to allow enhanced visualization of tissues.	Radiopaque Media,Contrast Agent,Contrast Agents,Contrast Material,Contrast Materials,Radiocontrast Agent,Radiocontrast Agents,Radiocontrast Media,Agent, Contrast,Agent, Radiocontrast,Agents, Contrast,Agents, Radiocontrast,Material, Contrast,Materials, Contrast,Media, Contrast,Media, Radiocontrast,Media, Radiopaque
D004285	Dogs	The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)	Canis familiaris,Dog
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia