Biomaterial Database

Comparison of the growth of the tunica media of the ascending aorta, aortic isthmus and descending aorta in infants and children. 1983

H van Meurs-van Woezik, and H W Klein, and L Markus-Silvis, and P Krediet

This study concerns the normal histological growth of the aorta in infants and children. We measured, in post mortem material consisting of 69 hearts and great vessels of infants and children who died from non-vascular diseases, the internal diameters of the ascending aorta, aortic isthmus and descending aorta together with the thickness of the tunica media and the packing density of its elastic fibres. Age range was from 27 weeks of gestational age up to 10 years after birth. The growth of the tunica media of the ascending aorta was, in part, different from that of the aortic isthmus and descending aorta. Notwithstanding an increase in the thickness of the tunica media parallelling, in all three parts of the aorta, an increase in their internal diameters, the packing density of the elastic fibres of the tunica media of the aortic isthmus and of the descending aorta showed no tendency to increase with age. However, the packing density of the elastic fibres of the ascending aorta showed a continuing increase with age parallelling the increase of the internal diameter. This can probably be better explained as a result of functional difference than as a result of different embryological origin.

UI	MeSH Term	Description	Entries
D007223	Infant	A child between 1 and 23 months of age.	Infants
D007231	Infant, Newborn	An infant during the first 28 days after birth.	Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D009131	Muscle, Smooth, Vascular	The nonstriated involuntary muscle tissue of blood vessels.	Vascular Smooth Muscle,Muscle, Vascular Smooth,Muscles, Vascular Smooth,Smooth Muscle, Vascular,Smooth Muscles, Vascular,Vascular Smooth Muscles
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D002675	Child, Preschool	A child between the ages of 2 and 5.	Children, Preschool,Preschool Child,Preschool Children
D004547	Elastic Tissue	Connective tissue comprised chiefly of elastic fibers. Elastic fibers have two components: ELASTIN and MICROFIBRILS.	Elastic Fibers,Elastic Fiber,Elastic Tissues,Fiber, Elastic,Fibers, Elastic,Tissue, Elastic,Tissues, Elastic
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001011	Aorta	The main trunk of the systemic arteries.	Aortas
D001013	Aorta, Thoracic	The portion of the descending aorta proceeding from the arch of the aorta and extending to the DIAPHRAGM, eventually connecting to the ABDOMINAL AORTA.	Aorta, Ascending,Aorta, Descending,Aortic Arch,Aortic Root,Arch of the Aorta,Descending Aorta,Sinotubular Junction,Ascending Aorta,Thoracic Aorta,Aortic Roots,Arch, Aortic,Ascending Aortas,Junction, Sinotubular,Root, Aortic,Sinotubular Junctions