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Serologic titres were measured to a number of micro-organisms in patients with systemic lupus erythematosus, their consanguineous and nonconsanguineous relatives and a group of control subjects. There was no significant difference in titres observed for any of the organisms in the different subject groups. The significance of these results is discussed. Despite the negative results, an infective aetiology for systemic lupus erythematosus remains a viable hypothesis.
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