Effect of velocity of distribution on red cell distribution in capillary blood vessels. 1978

R T Yen, and Y C Fung

Through the use of simulated model experiments, data on blood cell distribution into a bifurcating capillary blood vessel are obtained. The results show that the movement of red blood cells at a bifurcation point is influenced by the difference in velocities of flow in the daughter branches. If the velocity of flow in one branch is slower than that in the other, the hematocrit decreases in the slower branch and increases in the faster branch. For velocity ratios sufficiently smaller than a certain critical value, the hematocrit ratio can be expressed by a linear relationship, (H1/H2) - 1 = a[v1/v2) - 1], in which v1, v2 and H1 H2 denote the particle velocities and tube hematocritis in the branches 1 and 2, respectively, and a is a dimensionless contant dependent upon a number of factors, the most important of which are the ratio of cell diameter to tube diameter, the shape and rigidity of the pellets, and the hematocrit in the feeding tube. For velocity ratios beyond a critical value, nearly all the cells flow into the faster branch. The smaller the feeding-tube hematocrit is, the smaller is the critical velocity ratio at which this phenomenon occurs.

UI MeSH Term Description Entries
D008433 Mathematics The deductive study of shape, quantity, and dependence. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed) Mathematic
D008954 Models, Biological Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment. Biological Model,Biological Models,Model, Biological,Models, Biologic,Biologic Model,Biologic Models,Model, Biologic
D012039 Regional Blood Flow The flow of BLOOD through or around an organ or region of the body. Blood Flow, Regional,Blood Flows, Regional,Flow, Regional Blood,Flows, Regional Blood,Regional Blood Flows
D001783 Blood Flow Velocity A value equal to the total volume flow divided by the cross-sectional area of the vascular bed. Blood Flow Velocities,Flow Velocities, Blood,Flow Velocity, Blood,Velocities, Blood Flow,Velocity, Blood Flow
D002196 Capillaries The minute vessels that connect arterioles and venules. Capillary Beds,Sinusoidal Beds,Sinusoids,Bed, Sinusoidal,Beds, Sinusoidal,Capillary,Capillary Bed,Sinusoid,Sinusoidal Bed
D004912 Erythrocytes Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN. Blood Cells, Red,Blood Corpuscles, Red,Red Blood Cells,Red Blood Corpuscles,Blood Cell, Red,Blood Corpuscle, Red,Erythrocyte,Red Blood Cell,Red Blood Corpuscle
D006400 Hematocrit The volume of packed RED BLOOD CELLS in a blood specimen. The volume is measured by centrifugation in a tube with graduated markings, or with automated blood cell counters. It is an indicator of erythrocyte status in disease. For example, ANEMIA shows a low value; POLYCYTHEMIA, a high value. Erythrocyte Volume, Packed,Packed Red-Cell Volume,Erythrocyte Volumes, Packed,Hematocrits,Packed Erythrocyte Volume,Packed Erythrocyte Volumes,Packed Red Cell Volume,Packed Red-Cell Volumes,Red-Cell Volume, Packed,Red-Cell Volumes, Packed,Volume, Packed Erythrocyte,Volume, Packed Red-Cell,Volumes, Packed Erythrocyte,Volumes, Packed Red-Cell

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