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Maternal prolactin, cortisol, growth hormone and noradrenalin levels were measured immediately before induced labor, during the expulsion stage and 60-90 min following delivery in 10 normal subjects between 38 and 41 wk of gestation. A significant reduction in prolactin levels was accompanied by a marked rise in cortisol and noradrenalin levels, indicating a paradoxical suppression of prolactin due to stress of labor. Growth hormone levels declined both during labor and following delivery, presumably as a result of anti-insulin actions of cortisol and noradrenalin.
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