Rapid separation of 5-phospho-alpha-D-ribose-1-diphosphate from its metabolic derivatives.
1978
R K Goitein, and
S M Parsons
UI
MeSH Term
Description
Entries
D010428
Pentosephosphates
D010754
Phosphoribosyl Pyrophosphate
The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
Pyrophosphate, Phosphoribosyl
D002852
Chromatography, Ion Exchange
Separation technique in which the stationary phase consists of ion exchange resins. The resins contain loosely held small ions that easily exchange places with other small ions of like charge present in solutions washed over the resins.
An enzyme that catalyzes the first step of the pathway for histidine biosynthesis in Salmonella typhimurium. ATP reacts reversibly with 5-phosphoribosyl-1-pyrophosphate to yield N-1-(5'-phosphoribosyl)-ATP and pyrophosphate. EC 2.4.2.17.
Phosphoribosyl-ATP Pyrophosphorylase,Phosphoribosyl ATP Pyrophosphorylase,Phosphoribosyltransferase, ATP,Pyrophosphorylase, Phosphoribosyl-ATP