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The image analysing method for automated cytologic prescreening is founded on the evaluation of epithelial cell nuclei in regularly stained and prepared smears. The technical equipment consists of a fast scanning microscope and a software-oriented computer. The device is able to isolate all objects present in the visual fields. Clumps, artefacts, detritus and other disturbing objects are eliminated. Among the cell nuclei the nonepithelial forms (histiocytes, leukocytes, lymphocytes) are distinguished from the epithelial ones. The latter are compared with a representative sample of normal epithelial cell nuclei, exactly classified by cytologists. All objects are described by 18 mathematically defined parameters. The results of classification is a statistical information on the probability of coincidence of an unknown case with the normal object sample. In addition the evaluation program provides the number of automatic isolated cell nuclei. By these informations it is possible to differentiate between positive (tumor-suspicious), negative and inadequate smears.
K D Kunze, and
W R Herrmann, and
W Meyer
August 1978,
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques,
K D Kunze, and
W R Herrmann, and
W Meyer
January 1976,
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society,
K D Kunze, and
W R Herrmann, and
W Meyer
January 1972,
Osterreichische Zeitschrift fur Erforschung und Bekampfung der Krebskrankheit,
K D Kunze, and
W R Herrmann, and
W Meyer
April 1956,
American journal of obstetrics and gynecology,
K D Kunze, and
W R Herrmann, and
W Meyer
May 1977,
Zeitschrift fur arztliche Fortbildung,
K D Kunze, and
W R Herrmann, and
W Meyer
May 1975,
Nederlands tijdschrift voor geneeskunde,
K D Kunze, and
W R Herrmann, and
W Meyer
June 1969,
American journal of obstetrics and gynecology,
K D Kunze, and
W R Herrmann, and
W Meyer
December 1997,
IEEE transactions on medical imaging,
K D Kunze, and
W R Herrmann, and
W Meyer
February 1980,
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
K D Kunze, and
W R Herrmann, and
W Meyer
June 1997,
Academic radiology,
