In transversal section of the neural-vascular sonplexes of the left and right coronary arteries stained after Weigert-Pahl taken from 20 men of the second mature (10 healthy, 10 died from the cardiac ischemic disease--CID) and from 20 aged men (10 healthy, 10 died from the CID), the number of nerves forming the adventitial arterial plexus, the number of myelin fibers of three classes in their composition have been calculated. The age involution of the coronary arteries neural connections has proved to be manifested as a decreased number of the nerves, total number of the myelin fibers in their composition, subsidence first of all in the number of middle and thick myelin transmitters. The CID is accompanied with an enhancement of natural (aged) phenomena of the arterial wall denervation. This is expressed as disappearance of highly specialized thick and middle myelin fibers, as rarefication of the cholinergic fibers network in the arterial adventitial plexus, that is ascertained by a comparative morphometry of the film preparations of the adventitia, stained after Gomori and Karnovsky--Roots (from 32 hearts of healthy mature and aged persons and patients with the CID). Changes in the number of the neural elements in the coronary arteries adventitial plexus determines certain new quantitative peculiarities in their innervational connections both in the process of the organism's ontogenesis and under conditions of the CID.