Biomaterial Database

Otosclerosis and sensorineural hearing loss. A clinical study. 1983

M C Hansen

A causal relationship between otosclerosis and sensorineural hearing loss is thought to exist. Forty-nine patients with unilateral otosclerosis were studied by comparing the bone conduction threshold in the otosclerotic ear to the bone conduction threshold in the uninvolved ear. This difference was analyzed using the paired Student's t test, and significant differences were found at 1,000, 2,000, and 4,000 Hz but not at 500 Hz. This effect on the higher frequencies may be due to a change in the motion mechanics of the basilar membrane and is greatest at the basal end of the cochlea.

UI	MeSH Term	Description	Entries
D010040	Otosclerosis	Formation of spongy bone in the labyrinth capsule which can progress toward the STAPES (stapedial fixation) or anteriorly toward the COCHLEA leading to conductive, sensorineural, or mixed HEARING LOSS. Several genes are associated with familial otosclerosis with varied clinical signs.	Otospongiosis,Otoscleroses,Otospongioses
D001844	Bone Conduction	Transmission of sound waves through vibration of bones in the SKULL to the inner ear (COCHLEA). By using bone conduction stimulation and by bypassing any OUTER EAR or MIDDLE EAR abnormalities, hearing thresholds of the cochlea can be determined. Bone conduction hearing differs from normal hearing which is based on air conduction stimulation via the EAR CANAL and the TYMPANIC MEMBRANE.	Bone Conduction Hearing,Conduction Hearing, Bone,Conduction, Bone,Hearing, Bone Conduction
D006319	Hearing Loss, Sensorineural	Hearing loss resulting from damage to the COCHLEA and the sensorineural elements which lie internally beyond the oval and round windows. These elements include the AUDITORY NERVE and its connections in the BRAINSTEM.	Deafness Neurosensory,Deafness, Neurosensory,Deafness, Sensoryneural,Neurosensory Deafness,Sensorineural Hearing Loss,Sensoryneural Deafness,Cochlear Hearing Loss,Hearing Loss, Cochlear,Deafnesses, Neurosensory,Deafnesses, Sensoryneural,Neurosensory Deafnesses,Sensoryneural Deafness,Sensoryneural Deafnesses
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001299	Audiometry	The testing of the acuity of the sense of hearing to determine the thresholds of the lowest intensity levels at which an individual can hear a set of tones. The frequencies between 125 and 8000 Hz are used to test air conduction thresholds and the frequencies between 250 and 4000 Hz are used to test bone conduction thresholds.	Audiometries