Biomaterial Database

[Stepping movements caused by stimulation of the cat spinal cord dorsolateral funiculus]. 1983

O V Kazennikov, and M L Shik, and G V Iakovleva

It has been demonstrated in experiments on mesencephalic cats that microstimulation of the dorsolateral funiculus (DLF) at any level (from C1 to L1) elicited stepping movements in the ipsilateral hind limb. The lesion of the DLF at the C2--C3 level interfered with provocation of the stepping from the more rostral part of the DLF. However, stimulation caudal to the lesion remained effective. Stimulation of the DLF at the C5--Th3 did not prevent the stepping from L1, whereas that at the Th13 level made L1 ineffective despite the fact that the stepping was provoked by stimulation at the Th12 level. After lesion of the DLF at the two sites (C2 and L1 levels) stimulation at any level (from C3 to Th13) continued provoking the stepping. However, after stimulation at the Th5 and L1 levels the lesion of an isolated DLF area appeared ineffective. The data obtained suggest that stimulation of the DLF can elicit the stepping of the hind limb through the propriospinal system, provided that the stimulated part of the DLF contains at least 8--12 intact segments.

UI	MeSH Term	Description	Entries
D008124	Locomotion	Movement or the ability to move from one place or another. It can refer to humans, vertebrate or invertebrate animals, and microorganisms.	Locomotor Activity,Activities, Locomotor,Activity, Locomotor,Locomotor Activities
D002415	Cats	The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)	Felis catus,Felis domesticus,Domestic Cats,Felis domestica,Felis sylvestris catus,Cat,Cat, Domestic,Cats, Domestic,Domestic Cat
D004558	Electric Stimulation	Use of electric potential or currents to elicit biological responses.	Stimulation, Electric,Electrical Stimulation,Electric Stimulations,Electrical Stimulations,Stimulation, Electrical,Stimulations, Electric,Stimulations, Electrical
D006614	Hindlimb	Either of two extremities of four-footed non-primate land animals. It usually consists of a FEMUR; TIBIA; and FIBULA; tarsals; METATARSALS; and TOES. (From Storer et al., General Zoology, 6th ed, p73)	Hindlimbs
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013116	Spinal Cord	A cylindrical column of tissue that lies within the vertebral canal. It is composed of WHITE MATTER and GRAY MATTER.	Coccygeal Cord,Conus Medullaris,Conus Terminalis,Lumbar Cord,Medulla Spinalis,Myelon,Sacral Cord,Thoracic Cord,Coccygeal Cords,Conus Medullari,Conus Terminali,Cord, Coccygeal,Cord, Lumbar,Cord, Sacral,Cord, Spinal,Cord, Thoracic,Cords, Coccygeal,Cords, Lumbar,Cords, Sacral,Cords, Spinal,Cords, Thoracic,Lumbar Cords,Medulla Spinali,Medullari, Conus,Medullaris, Conus,Myelons,Sacral Cords,Spinal Cords,Spinali, Medulla,Spinalis, Medulla,Terminali, Conus,Terminalis, Conus,Thoracic Cords

Related Publications

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Organization of the fibers in the dorsolateral funiculus of the cervical spinal cord in the cat.

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