-transparent.png){kind=logo}
Discrimination between the three clinical subtypes of Gaucher's disease based on the molecular forms of beta-glucocerebrosidase detected by monoclonal antibody is described. In normal fibroblast extracts, cross-reacting material (CRM) to human placental glucocerebrosidase is detected at Mr approximately equal to 63 000, 61 000 and 56 000. In Type 1 Gaucher's disease, the major fibroblast CRM has a Mr approximately equal to 56 000,, with less CRM seen at 61 000 and 56 000. Type 3 fibroblast extracts have a single CRM form at Mr approximately equal to 63 000. No CRM is found in Type 2 Gaucher's disease fibroblasts with monoclonal antiglucocerebrosidase antibody 8E4.
Related Publications
E I Ginns, and
F P Tegelaers, and
R Barneveld, and
H Galjaard, and
A J Reuser, and
R O Brady, and
J M Tager, and
J A Barranger
January 1982,
Scandinavian journal of haematology,
E I Ginns, and
F P Tegelaers, and
R Barneveld, and
H Galjaard, and
A J Reuser, and
R O Brady, and
J M Tager, and
J A Barranger
August 1995,
Neurology,
E I Ginns, and
F P Tegelaers, and
R Barneveld, and
H Galjaard, and
A J Reuser, and
R O Brady, and
J M Tager, and
J A Barranger
January 1993,
Haematologica,
E I Ginns, and
F P Tegelaers, and
R Barneveld, and
H Galjaard, and
A J Reuser, and
R O Brady, and
J M Tager, and
J A Barranger
November 1987,
Harefuah,
E I Ginns, and
F P Tegelaers, and
R Barneveld, and
H Galjaard, and
A J Reuser, and
R O Brady, and
J M Tager, and
J A Barranger
December 1978,
Life sciences,
E I Ginns, and
F P Tegelaers, and
R Barneveld, and
H Galjaard, and
A J Reuser, and
R O Brady, and
J M Tager, and
J A Barranger
January 1987,
Journal of cancer research and clinical oncology,
E I Ginns, and
F P Tegelaers, and
R Barneveld, and
H Galjaard, and
A J Reuser, and
R O Brady, and
J M Tager, and
J A Barranger
April 1963,
Proceedings of the Royal Society of Medicine,
E I Ginns, and
F P Tegelaers, and
R Barneveld, and
H Galjaard, and
A J Reuser, and
R O Brady, and
J M Tager, and
J A Barranger
August 1952,
The Journal of bone and joint surgery. British volume,
E I Ginns, and
F P Tegelaers, and
R Barneveld, and
H Galjaard, and
A J Reuser, and
R O Brady, and
J M Tager, and
J A Barranger
March 1987,
Vnitrni lekarstvi,
E I Ginns, and
F P Tegelaers, and
R Barneveld, and
H Galjaard, and
A J Reuser, and
R O Brady, and
J M Tager, and
J A Barranger
February 1992,
Therapeutic drug monitoring,
