BIOMAT Database Logo BIOMAT Database Logo

Prevalence of deficits of complement components in patients with recurrent meningococcal infections. 1983

J Merino, and V Rodriguez-Valverde, and J A Lamelas, and J L Riestra, and B Casanueva

UI MeSH Term Description Entries
D008589 Meningococcal Infections Infections with bacteria of the species NEISSERIA MENINGITIDIS. Meningococcal Septicemia,Infections, Meningococcal,Meningococcal Disease,Infection, Meningococcal,Meningococcal Diseases,Meningococcal Infection,Septicemia, Meningococcal
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D012008 Recurrence The return of a sign, symptom, or disease after a remission. Recrudescence,Relapse,Recrudescences,Recurrences,Relapses
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D003165 Complement System Proteins Serum glycoproteins participating in the host defense mechanism of COMPLEMENT ACTIVATION that creates the COMPLEMENT MEMBRANE ATTACK COMPLEX. Included are glycoproteins in the various pathways of complement activation (CLASSICAL COMPLEMENT PATHWAY; ALTERNATIVE COMPLEMENT PATHWAY; and LECTIN COMPLEMENT PATHWAY). Complement Proteins,Complement,Complement Protein,Hemolytic Complement,Complement, Hemolytic,Protein, Complement,Proteins, Complement,Proteins, Complement System
D003176 Complement C3 A glycoprotein that is central in both the classical and the alternative pathway of COMPLEMENT ACTIVATION. C3 can be cleaved into COMPLEMENT C3A and COMPLEMENT C3B, spontaneously at low level or by C3 CONVERTASE at high level. The smaller fragment C3a is an ANAPHYLATOXIN and mediator of local inflammatory process. The larger fragment C3b binds with C3 convertase to form C5 convertase. C3 Complement,C3 Precursor,Complement 3,Complement C3 Precursor,Complement Component 3,Precursor-Complement 3,Pro-C3,Pro-Complement 3,C3 Precursor, Complement,C3, Complement,Complement, C3,Component 3, Complement,Precursor Complement 3,Precursor, C3,Precursor, Complement C3,Pro C3,Pro Complement 3
D003185 Complement C8 A 150-kDa serum glycoprotein composed of three subunits with each encoded by a different gene (C8A; C8B; and C8G). This heterotrimer contains a disulfide-linked C8alpha-C8gamma heterodimer and a noncovalently associated C8beta chain. C8 is the next component to bind the C5-7 complex forming C5b-8 that binds COMPLEMENT C9 and acts as a catalyst in the polymerization of C9. C8 Complement,Complement 8,Complement Component 8,Complement Component C8 alpha,Complement Component C8 alpha Chain,Complement Component C8 beta,Complement Component C8 beta Chain,Complement Component C8 gamma,Complement Component C8 gamma Chain,C8, Complement,Complement, C8,Component 8, Complement
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

Related Publications

J Merino, and V Rodriguez-Valverde, and J A Lamelas, and J L Riestra, and B Casanueva
Deficiency of late complement components in patients with severe and recurrent meningococcal infections.
August 1996, European journal of pediatrics,
J Merino, and V Rodriguez-Valverde, and J A Lamelas, and J L Riestra, and B Casanueva
Prevalence of complement deficiencies in children with systemic meningococcal infections.
January 1987, The Pediatric infectious disease journal,
J Merino, and V Rodriguez-Valverde, and J A Lamelas, and J L Riestra, and B Casanueva
Systemic meningococcal infections in patients with acquired complement deficiency.
February 1993, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology,
J Merino, and V Rodriguez-Valverde, and J A Lamelas, and J L Riestra, and B Casanueva
Familial deficiency of the seventh component of complement associated with recurrent meningococcal infections.
August 1989, European journal of pediatrics,
J Merino, and V Rodriguez-Valverde, and J A Lamelas, and J L Riestra, and B Casanueva
Low prevalence of complement deficiencies among patients with meningococcal disease in Norway.
April 1993, Scandinavian journal of immunology,
J Merino, and V Rodriguez-Valverde, and J A Lamelas, and J L Riestra, and B Casanueva
Recurrent meningococcal infections associated with a functional deficiency of the C8 component of human complement.
January 1980, Clinical and experimental immunology,
J Merino, and V Rodriguez-Valverde, and J A Lamelas, and J L Riestra, and B Casanueva
Prevalence of congenital or acquired complement deficiency in patients with sporadic meningococcal disease.
April 1983, The New England journal of medicine,
J Merino, and V Rodriguez-Valverde, and J A Lamelas, and J L Riestra, and B Casanueva
[Familial complement deficiency in a patient with recurrent meningococcal sepsis].
December 1995, Medicina clinica,
J Merino, and V Rodriguez-Valverde, and J A Lamelas, and J L Riestra, and B Casanueva
Recurrent bacterial meningitis in patients with genetic defects of terminal complement components.
April 1980, Clinical and experimental immunology,
J Merino, and V Rodriguez-Valverde, and J A Lamelas, and J L Riestra, and B Casanueva
Complement C8 deficiency with recurrent meningococcemia: examination of meningococcal opsonization.
August 1985, Australian paediatric journal,
Copied contents to your clipboard!