Biomaterial Database

[Evaluation of pulmonary function parameters in twins]. 1982

A Shida

The purpose of this study was to determine the role of genetic influence on the variability of pulmonary function tests in normal individuals. Thirty-one pairs of twins (20 monozygotes (MZ) and 11 dizygotes (DZ) of both sexes, ranging in age from 15 to 18 years, were tested. Degree of similarity in each parameter was compared between MZ pairs and DZ pairs by within-pair variance ratio (MWDZ/MWMZ). The within-pair variances of MZ were smaller than DZ with respect to FVC, FEV1/FVC, V50, V25, delta N2 and FRC. These parameters were corrected for height; again the within-pair variances of MZ were smaller than DZ with respect to all the parameters except for FRC. The results indicate that these parameters were at least partly determined by genetic factor. However the within-pair variance of FEV1, PF, CV/VC, Raw, Pao2, Paco2, pH, and [HCO3-] were not different between the two groups. To estimate the similarity within MZ pairs, among-pair to within-pair variance ratio (MAMZ/MWMZ) were used. All the parameters of pulmonary mechanics showed similarity within pairs. Arterial pH and Pao2 also disclosed a significant similarity within-pairs, but Paco2 and [HCO3-] did not.

UI	MeSH Term	Description	Entries
D008168	Lung	Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood.	Lungs
D008297	Male		Males
D011247	Pregnancy	The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	Gestation,Pregnancies
D012129	Respiratory Function Tests	Measurement of the various processes involved in the act of respiration: inspiration, expiration, oxygen and carbon dioxide exchange, lung volume and compliance, etc.	Lung Function Tests,Pulmonary Function Tests,Function Test, Pulmonary,Function Tests, Pulmonary,Pulmonary Function Test,Test, Pulmonary Function,Tests, Pulmonary Function,Function Test, Lung,Function Test, Respiratory,Function Tests, Lung,Function Tests, Respiratory,Lung Function Test,Respiratory Function Test,Test, Lung Function,Test, Respiratory Function,Tests, Lung Function,Tests, Respiratory Function
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000886	Anthropometry	The technique that deals with the measurement of the size, weight, and proportions of the human or other primate body.
D014427	Twins	Two individuals derived from two FETUSES that were fertilized at or about the same time, developed in the UTERUS simultaneously, and born to the same mother. Twins are either monozygotic (TWINS, MONOZYGOTIC) or dizygotic (TWINS, DIZYGOTIC).	Twin
D014429	Twins, Dizygotic	Two offspring from the same PREGNANCY. They are from two OVA, fertilized at about the same time by two SPERMATOZOA. Such twins are genetically distinct and can be of different sexes.	Twins, Fraternal,Dizygotic Twin,Dizygotic Twins,Fraternal Twin,Fraternal Twins,Twin, Dizygotic,Twin, Fraternal