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A spectrum of changes that range from crypt basophilia through varying degrees of dysplasia and carcinoma in situ have been observed in the flat, nonraised mucosa of the rectum in patient who received pelvic irradiation for carcinoma of the cervix. This case demonstrates (1) the morphological evidence of the relationship between radiation and large-bowel carcinoma, (2) that large-bowel carcinoma may arise directly from the flat mucosa without having to go through a benign polyp-cancer sequence, (3) that early carcinoma arising from the flat mucosa may clinically resemble radiation proctocolitis, and therefore, (4) that increased vigilance in needed for the follow-up of patients who undergo pelvic irradiation.
A K Shamsuddin, and
E G Elias
July 1981,
Endoscopy,
A K Shamsuddin, and
E G Elias
March 2006,
International journal of radiation oncology, biology, physics,
A K Shamsuddin, and
E G Elias
August 1989,
Gastroenterology,
A K Shamsuddin, and
E G Elias
August 1982,
The Journal of the Dental Association of South Africa = Die Tydskrif van die Tandheelkundige Vereniging van Suid-Afrika,
A K Shamsuddin, and
E G Elias
January 1967,
Pathologica,
A K Shamsuddin, and
E G Elias
November 1992,
The Journal of pathology,
A K Shamsuddin, and
E G Elias
October 2002,
Oral oncology,
A K Shamsuddin, and
E G Elias
August 1997,
Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology,
A K Shamsuddin, and
E G Elias
September 1989,
Tandlaegebladet,
A K Shamsuddin, and
E G Elias
June 1997,
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology,
