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A strain of Claviceps purpurea, designated Pepty 695/S produces ergotoxine alkaloids under particular conditions of fermentation. The onset of alkaloid synthesis occurs around the second day of cultivation. Alkaloid formation is connected with morphological and ultrastructural changes. In the first 3-5 days of cultivation short thickened, septated hyphae, organized in plectenchymatic pellets as well as large single cells are formed. The hyphae are ultrastructurally characterized by increasing number of lipid droplets, deposits of glycogen and by extended ER membranes, which apparently may form numerous vesicles. The correlations between lipid and alkaloid synthesis are discussed.
W Lösecke, and
D Neumann, and
H P Schmauder, and
D Gröger
March 1966,
Nature,
W Lösecke, and
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D Gröger
January 1975,
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W Lösecke, and
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January 1975,
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W Lösecke, and
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January 1969,
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W Lösecke, and
D Neumann, and
H P Schmauder, and
D Gröger
January 1957,
Schweizerische Zeitschrift fur Pathologie und Bakteriologie. Revue suisse de pathologie et de bacteriologie,
W Lösecke, and
D Neumann, and
H P Schmauder, and
D Gröger
February 1976,
Experientia,
W Lösecke, and
D Neumann, and
H P Schmauder, and
D Gröger
June 1966,
Experientia,
W Lösecke, and
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H P Schmauder, and
D Gröger
January 1974,
Folia microbiologica,
W Lösecke, and
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H P Schmauder, and
D Gröger
May 1977,
Canadian journal of microbiology,
W Lösecke, and
D Neumann, and
H P Schmauder, and
D Gröger
February 1957,
Canadian journal of microbiology,
