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Electron probe X-ray microanalysis in the scanning microscope was used to determine the elemental composition of muscle fibres from patients with rheumatoid arthritis (RA). Quantitative data concerning phosphorus, sulphur, chlorine and potassium were correlated to the fibre type by a routine method based on serial cryosectioning and histochemical staining of adjacent sections. Significantly lowered sulphur values were found in type II A and II B muscle fibres of RA patients as compared to those of healthy controls. Traces of gold were detected in muscles of two patients treated with gold salts. The basis and mechanism for the decreased sulphur content in RA muscles are so far unknown, but may depend on the decreased amount of sulphur-rich potein(s).
R Wróblewski, and
W Gremski, and
R Nordemar, and
L Edström
May 1978,
Histochemistry,
R Wróblewski, and
W Gremski, and
R Nordemar, and
L Edström
March 1974,
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society,
R Wróblewski, and
W Gremski, and
R Nordemar, and
L Edström
December 1987,
Journal of biochemical and biophysical methods,
R Wróblewski, and
W Gremski, and
R Nordemar, and
L Edström
July 1981,
Klinische Wochenschrift,
R Wróblewski, and
W Gremski, and
R Nordemar, and
L Edström
November 2003,
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc,
R Wróblewski, and
W Gremski, and
R Nordemar, and
L Edström
January 1986,
Annals of the New York Academy of Sciences,
R Wróblewski, and
W Gremski, and
R Nordemar, and
L Edström
December 1970,
Science (New York, N.Y.),
R Wróblewski, and
W Gremski, and
R Nordemar, and
L Edström
February 1996,
Experimental eye research,
R Wróblewski, and
W Gremski, and
R Nordemar, and
L Edström
January 1990,
Stomatologiia,
R Wróblewski, and
W Gremski, and
R Nordemar, and
L Edström
January 1982,
Archives of environmental contamination and toxicology,
