[Determination of the serum protein concentration based on the measurement of density by the mechanical oscillator technique (author's transl)]. 1978

H Holzer, and H Leopold, and H Hinghofer-Szalkay, and H Stübchen-Kirchner, and E Maurer

A linear relation is well established between the density and protein concentration of the serum. The measurement of protein concentration by a new technique for the determination of the absolute density, the mechanical oscillator technique, was investigated. The method is based on the determination of the resonant frequency of a mechanical bending-type, U-shaped glass tube oscillator filled with the sample. The shift in the resonant frequency of the oscillator caused by the mass of the defined volume of the sample taking part in the vibration can be used to calculate the density or protein concentration of the sample. In spite of the low specificity of the method, the interference of substances like glucose, urea or triglycerides is small. Simplicity and rapid results of high accuracy recommend the mechanical oscillator technique for the routine laboratory.

UI MeSH Term Description Entries
D008722 Methods A series of steps taken in order to conduct research. Techniques,Methodological Studies,Methodological Study,Procedures,Studies, Methodological,Study, Methodological,Method,Procedure,Technique
D009991 Oscillometry The measurement of frequency or oscillation changes. Oscillometries
D001786 Blood Glucose Glucose in blood. Blood Sugar,Glucose, Blood,Sugar, Blood
D001798 Blood Proteins Proteins that are present in blood serum, including SERUM ALBUMIN; BLOOD COAGULATION FACTORS; and many other types of proteins. Blood Protein,Plasma Protein,Plasma Proteins,Serum Protein,Serum Proteins,Protein, Blood,Protein, Plasma,Protein, Serum,Proteins, Blood,Proteins, Plasma,Proteins, Serum
D014280 Triglycerides An ester formed from GLYCEROL and three fatty acid groups. Triacylglycerol,Triacylglycerols,Triglyceride
D014508 Urea A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids. Basodexan,Carbamide,Carmol

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