The authors develop a retrospective investigation about 97 arterio-venous fistulae performed on acute and chronic uraemic patients for hemodialytic purposes. The method followed by the authors is to surgically insert a cannula in the femoral vein in case of urgency, and to prevailingly perform arterio-venous fistulae in the chronic uraemic patients' wrist. In the cases of difficult vascular access, the authors perform an autologous graft of large saphena vein to upper limb, between sublacertic umeral artery and cephalic or basilic median vein, and describe its technique.