-transparent.png){kind=logo}
We have undertaken a perspective study of the prevelance of the central nervous disease in acute granulocytic leukemia (AGL). Thirty-nine newly diagnosed patients with AGL underwent cytocentrifuge examination of cerebral spinal fluid. Seven of the 39 patients had blast cells in their cerebral spinal fluid. All seven of these patients had acute myelomonocytic leukemia (AMML). No patients with other variants of AGL demonstrated blast cells in their cerebral spinal fluid. Other high risk factors associated with meningeal infiltration were elevated serum lysozyme levels, high peripheral white blood cell count, low age, splemomegaly and the presence of infiltration in other organs. The admission rates for patients with meningeal leukemia were lower and the survival time was shorter than in both the 32 noninvolved patients and the noninvolved patients with AMML. We believe that a lumbar puncture is indicated in all patients with newly diagnosed AMML.
R J Meyer, and
P P Ferreira, and
J Cuttner, and
M L Greenberg, and
J Goldberg, and
J F Holland
April 2010,
Pediatric blood & cancer,
R J Meyer, and
P P Ferreira, and
J Cuttner, and
M L Greenberg, and
J Goldberg, and
J F Holland
February 2010,
Leukemia & lymphoma,
R J Meyer, and
P P Ferreira, and
J Cuttner, and
M L Greenberg, and
J Goldberg, and
J F Holland
September 1987,
The American journal of medicine,
R J Meyer, and
P P Ferreira, and
J Cuttner, and
M L Greenberg, and
J Goldberg, and
J F Holland
January 1955,
Acta medica Philippina,
R J Meyer, and
P P Ferreira, and
J Cuttner, and
M L Greenberg, and
J Goldberg, and
J F Holland
May 1978,
Acta neuropathologica,
R J Meyer, and
P P Ferreira, and
J Cuttner, and
M L Greenberg, and
J Goldberg, and
J F Holland
January 2019,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
R J Meyer, and
P P Ferreira, and
J Cuttner, and
M L Greenberg, and
J Goldberg, and
J F Holland
March 1984,
Gan no rinsho. Japan journal of cancer clinics,
R J Meyer, and
P P Ferreira, and
J Cuttner, and
M L Greenberg, and
J Goldberg, and
J F Holland
January 1979,
Harefuah,
R J Meyer, and
P P Ferreira, and
J Cuttner, and
M L Greenberg, and
J Goldberg, and
J F Holland
April 1972,
Israel journal of medical sciences,
R J Meyer, and
P P Ferreira, and
J Cuttner, and
M L Greenberg, and
J Goldberg, and
J F Holland
June 1986,
Tumori,
