-transparent.png){kind=logo}
Body weight gain and food and water consumption of female rats receiving daily methadone injections (5 mg/kg) intraperitoneally prior to mating and during gestation and lactation were studied. In contrast to saline-injected mothers, methadone-treated females had lower body weights throughout pregnancy, but gained weight during lactation; by postnatal day 21, both groups were of comparable body weight. No significant differences in food consumption throughout gestation or lactation were recorded. Total water consumption of methadone-treated rats was higher during the first 2 weeks of gestation and lactation, and lower during the 3rd week of lactation when compared to controls. These results demonstrate that methadone-treated rats have lower body weights throughout gestation and lactation, and that these weight deficits are not caused by insufficient food and water consumption.
W J White, and
P J McLaughlin, and
I S Zagon
April 1994,
Psychopharmacology,
W J White, and
P J McLaughlin, and
I S Zagon
January 1987,
Physiology & behavior,
W J White, and
P J McLaughlin, and
I S Zagon
January 1984,
Psychopharmacology,
W J White, and
P J McLaughlin, and
I S Zagon
January 1986,
Psychopharmacology,
W J White, and
P J McLaughlin, and
I S Zagon
January 1990,
Life sciences,
W J White, and
P J McLaughlin, and
I S Zagon
January 1983,
The International journal of neuroscience,
W J White, and
P J McLaughlin, and
I S Zagon
July 1994,
Jikken dobutsu. Experimental animals,
W J White, and
P J McLaughlin, and
I S Zagon
May 1987,
Pharmacology, biochemistry, and behavior,
W J White, and
P J McLaughlin, and
I S Zagon
January 1987,
General pharmacology,
W J White, and
P J McLaughlin, and
I S Zagon
January 1959,
Nature,
