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Five cases of acute myeloblastic leukaemia (AML) arising in the course of non-Hodgkin's lymphoma (NHL) are described. The initial lymphoma was nodular lymphoid poorly differentiated in 4 cases. All patients were under chemotherapy for at least 28 months, and 3 of them were irradiated. AML was diagnosed 44 to 78 months after NHL and was heralded in 3 cases by a preleukaemia phase of pancytopenia. The leukaemia was typically myeloblastic in 2 cases and difficult to classify in 3 cases. Death occurred rapidly in 4 patients. The actuarial risk was 4.5% at 5 years. Since AML's occur mainly in NHL's, the management of this type of lymphoma with favourable prognosis ought to be reevaluated.
J L Harousseau, and
J M Andrieu, and
J Dumont, and
B Montagnon, and
B Asselain, and
M T Daniel, and
G Flandrin
July 1979,
British medical journal,
J L Harousseau, and
J M Andrieu, and
J Dumont, and
B Montagnon, and
B Asselain, and
M T Daniel, and
G Flandrin
July 1977,
Deutsche medizinische Wochenschrift (1946),
J L Harousseau, and
J M Andrieu, and
J Dumont, and
B Montagnon, and
B Asselain, and
M T Daniel, and
G Flandrin
August 1974,
Deutsche medizinische Wochenschrift (1946),
J L Harousseau, and
J M Andrieu, and
J Dumont, and
B Montagnon, and
B Asselain, and
M T Daniel, and
G Flandrin
April 1981,
La Nouvelle presse medicale,
J L Harousseau, and
J M Andrieu, and
J Dumont, and
B Montagnon, and
B Asselain, and
M T Daniel, and
G Flandrin
January 1981,
Bulletin du cancer,
J L Harousseau, and
J M Andrieu, and
J Dumont, and
B Montagnon, and
B Asselain, and
M T Daniel, and
G Flandrin
November 1978,
Rontgen-Blatter; Zeitschrift fur Rontgen-Technik und medizinisch-wissenschaftliche Photographie,
J L Harousseau, and
J M Andrieu, and
J Dumont, and
B Montagnon, and
B Asselain, and
M T Daniel, and
G Flandrin
March 1981,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
J L Harousseau, and
J M Andrieu, and
J Dumont, and
B Montagnon, and
B Asselain, and
M T Daniel, and
G Flandrin
October 1980,
Deutsche medizinische Wochenschrift (1946),
J L Harousseau, and
J M Andrieu, and
J Dumont, and
B Montagnon, and
B Asselain, and
M T Daniel, and
G Flandrin
July 1979,
Deutsche medizinische Wochenschrift (1946),
J L Harousseau, and
J M Andrieu, and
J Dumont, and
B Montagnon, and
B Asselain, and
M T Daniel, and
G Flandrin
February 1978,
Fukuoka igaku zasshi = Hukuoka acta medica,
