Legionnaires' disease and other newly recognized Legionella-like causes of bacterial pneumonia. 1980

R L Myerowitz

Three "new" pneumonias have recently been recognized which are old diseases whose etiology has only been newly-recognized. Legionella pneumophila (Legionnaires' disease), Pittsburgh Pneumonia Agent (PPA), and Legionella-like Organisms (the Family Legionellaceae) are "rickettsia-like" bacteria which require special media for cultivation. They can each cause nosocomial pneumonia in immunosuppressed patients and all but PPA cause community-acquired pneumonia. The Legionellaceae reside in the environment within water and soil. Diagnosis can be established by morphologic, microbiological, and immunologic analysis of respiratory secretions or lung tissue. It may be confirmed retrospectively by serology. Legionella pneumophila and PPA are susceptible to erythromycin and rifampin; erythromycin is the current drug of choice for treatment of these diseases.

UI MeSH Term Description Entries
D007877 Legionnaires' Disease An acute, sometimes fatal, pneumonia-like bacterial infection characterized by high fever, malaise, muscle aches, respiratory disorders and headache. It is named for an outbreak at the 1976 Philadelphia convention of the American Legion. Legionella pneumophila Infections,Infections, Legionella pneumophila,Legionnaire Disease,Pontiac Fever,Disease, Legionnaire,Disease, Legionnaires',Fever, Pontiac,Infection, Legionella pneumophila,Legionella pneumophila Infection,Legionnaire's Disease,Legionnaires Disease
D011014 Pneumonia Infection of the lung often accompanied by inflammation. Experimental Lung Inflammation,Lobar Pneumonia,Lung Inflammation,Pneumonia, Lobar,Pneumonitis,Pulmonary Inflammation,Experimental Lung Inflammations,Inflammation, Experimental Lung,Inflammation, Lung,Inflammation, Pulmonary,Inflammations, Lung,Inflammations, Pulmonary,Lobar Pneumonias,Lung Inflammation, Experimental,Lung Inflammations,Lung Inflammations, Experimental,Pneumonias,Pneumonias, Lobar,Pneumonitides,Pulmonary Inflammations
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

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