-transparent.png){kind=logo}
Cholesterol oxidase (3 beta-hydrosteroid oxidase), isolated from Actinomyces lavendulae, oxidized unesterified cholesterol in rabbit blood serum without detergents in vitro. Intravenous administration of the enzyme into hypercholesterolemic rabbits at a dose of 0.5-2.0 un/kg decrease distinctly the cholesterol content in blood. The rate of the decrease depended on the dose of the preparation. Acute toxicity of the cholesterol oxidase preparations for mice correlated with the degree of purification of the enzyme. Cholesterol oxidase from Act. lavendulae may be considered as a potential hypocholesterolemic drug.
Related Publications
A V Titov, and
V V Slobodskaia, and
E V Tarasova, and
I M Tereshin
January 1982,
Nauchnye doklady vysshei shkoly. Biologicheskie nauki,
A V Titov, and
V V Slobodskaia, and
E V Tarasova, and
I M Tereshin
January 1987,
Artery,
A V Titov, and
V V Slobodskaia, and
E V Tarasova, and
I M Tereshin
June 1984,
Biulleten' eksperimental'noi biologii i meditsiny,
A V Titov, and
V V Slobodskaia, and
E V Tarasova, and
I M Tereshin
July 1953,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
A V Titov, and
V V Slobodskaia, and
E V Tarasova, and
I M Tereshin
April 1991,
Atherosclerosis,
A V Titov, and
V V Slobodskaia, and
E V Tarasova, and
I M Tereshin
December 1979,
The Journal of nutrition,
A V Titov, and
V V Slobodskaia, and
E V Tarasova, and
I M Tereshin
January 1986,
Patologicheskaia fiziologiia i eksperimental'naia terapiia,
A V Titov, and
V V Slobodskaia, and
E V Tarasova, and
I M Tereshin
April 1959,
Medicina espanola,
A V Titov, and
V V Slobodskaia, and
E V Tarasova, and
I M Tereshin
October 1954,
Angiology,
A V Titov, and
V V Slobodskaia, and
E V Tarasova, and
I M Tereshin
June 1970,
The Journal of laboratory and clinical medicine,
