Redistribution of platelets during discontinous flow platelet pheresis. 1978

A J Katz, and R F Reiss, and J A Houx

Greater numbers of platelets are recovered during discontinuous flow centrifugation than can be simply accounted for by the decrease in total circulating platelets in the donor. There is a linear relationship between the logarithm of the circulating platelet count and the number of plateletpheresis bowls filled. The disappearance of platelets from the peripheral circulation occurs at a greater rate in splenectomized donors than in normal donors, and the rate of platelet disappearance in normal donors is less than what would be expected if there were no in vivo platelet storage pools. The data suggest the redistribution of platelets from the spleen in normal donors during the time course of the procedure.

UI MeSH Term Description Entries
D007700 Kinetics The rate dynamics in chemical or physical systems.
D008297 Male Males
D010983 Plateletpheresis The preparation of platelet concentrates with the return of red cells and platelet-poor plasma to the donor. Blood Plateletpheresis,Thrombocytapheresis,Thrombocytopheresis,Blood Plateletphereses,Plateletphereses,Plateletphereses, Blood,Plateletpheresis, Blood,Thrombocytaphereses,Thrombocytophereses
D001792 Blood Platelets Non-nucleated disk-shaped cells formed in the megakaryocyte and found in the blood of all mammals. They are mainly involved in blood coagulation. Platelets,Thrombocytes,Blood Platelet,Platelet,Platelet, Blood,Platelets, Blood,Thrombocyte
D001803 Blood Transfusion The introduction of whole blood or blood component directly into the blood stream. (Dorland, 27th ed) Blood Transfusions,Transfusion, Blood,Transfusions, Blood
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013156 Splenectomy Surgical procedure involving either partial or entire removal of the spleen. Splenectomies

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