Biomaterial Database

Auditory brainstem responses and masking level differences from persons with brainstem lesion. 1982

D Noffsinger, and C D Martinez, and A B Schaefer

Twenty subjects with abnormal auditory brainstem responses (ABR) and diagnosed brainstem lesion or disease were studied. Normal listeners were used as controls. The objective of the project was to examine the relationship of the particular ABR patterns exhibited by these subjects to the binaural masking level differences (MLD) and transbrainstem acoustic reflex (AR) patterns yielded by the same subjects. Patients whose ABR abnormalities commenced with brainstem potentials I, II, or III had small or no MLD and absent or abnormal AR. Patients whose ABR abnormalities commenced with brainstem potentials IV or V yielded normal MLD and AR behavior. Most important, these findings suggest that MLD size is influenced by activity which also contributes importantly to the development of the early auditory brainstem potentials.

UI	MeSH Term	Description	Entries
D008144	Loudness Perception	The perceived attribute of a sound which corresponds to the physical attribute of intensity.	Loudness Perceptions,Perception, Loudness,Perceptions, Loudness
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D010470	Perceptual Masking	The interference of one perceptual stimulus with another causing a decrease or lessening in perceptual effectiveness.	Masking, Perceptual,Maskings, Perceptual,Perceptual Maskings
D010898	Pitch Perception	A dimension of auditory sensation varying with cycles per second of the sound stimulus.	Perception, Pitch,Perceptions, Pitch,Pitch Perceptions
D012022	Reflex, Acoustic	Intra-aural contraction of tensor tympani and stapedius in response to sound.	Acoustic Reflex
D001927	Brain Diseases	Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.	Intracranial Central Nervous System Disorders,Brain Disorders,CNS Disorders, Intracranial,Central Nervous System Disorders, Intracranial,Central Nervous System Intracranial Disorders,Encephalon Diseases,Encephalopathy,Intracranial CNS Disorders,Brain Disease,Brain Disorder,CNS Disorder, Intracranial,Encephalon Disease,Encephalopathies,Intracranial CNS Disorder
D001933	Brain Stem	The part of the brain that connects the CEREBRAL HEMISPHERES with the SPINAL CORD. It consists of the MESENCEPHALON; PONS; and MEDULLA OBLONGATA.	Brainstem,Truncus Cerebri,Brain Stems,Brainstems,Cerebri, Truncus,Cerebrus, Truncus,Truncus Cerebrus
D003389	Cranial Nerve Diseases	Disorders of one or more of the twelve cranial nerves. With the exception of the optic and olfactory nerves, this includes disorders of the brain stem nuclei from which the cranial nerves originate or terminate.	Cranial Neuropathies,Cranial Neuropathies, Multiple,Neuropathies, Cranial,Cranial Nerve Disorders,Cranial Nerve Palsies,Nervus Cranialis Disorders,Cranial Nerve Disease,Cranial Nerve Disorder,Cranial Nerve Palsy,Cranial Neuropathy,Cranial Neuropathy, Multiple,Multiple Cranial Neuropathies,Multiple Cranial Neuropathy,Nervus Cranialis Disorder,Neuropathies, Multiple Cranial,Neuropathy, Cranial,Neuropathy, Multiple Cranial,Palsies, Cranial Nerve,Palsy, Cranial Nerve
D005260	Female		Females