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The reliability of a radioimmunometric assay of serum ferritin concentration by a packaged kit was evaluated. In addition, application of the serum ferritin assay to the clinical evaluation of selected anemias was assessed. When appropriate serum dilutions were utilized, this method was sufficiently reproducible and reliable for application to the clinical laboratory. Serum ferritin was found to be a valuable tool in the differential diagnosis of anemia accompanied by hypoferremia, although iron depletion coexisting with either the anemia of chronic disease or active hepatocellular disease may not be clearly appreciated. The primary advantage of the determination was to help characterize the iron status of the patient with a hypochromic microcytic anemia or hypoferremia who would ordinarly require a bone-marrow examination for iron stores.
R G Sheehan, and
M J Newton, and
E P Frenkel
December 1979,
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
R G Sheehan, and
M J Newton, and
E P Frenkel
December 1981,
Kaku igaku. The Japanese journal of nuclear medicine,
R G Sheehan, and
M J Newton, and
E P Frenkel
December 1984,
Radioisotopes,
R G Sheehan, and
M J Newton, and
E P Frenkel
January 1978,
The Journal of nuclear medicine and allied sciences,
R G Sheehan, and
M J Newton, and
E P Frenkel
January 1981,
Acta haematologica,
R G Sheehan, and
M J Newton, and
E P Frenkel
February 1981,
Kaku igaku. The Japanese journal of nuclear medicine,
R G Sheehan, and
M J Newton, and
E P Frenkel
February 1985,
Radioisotopes,
R G Sheehan, and
M J Newton, and
E P Frenkel
November 1984,
Radioisotopes,
R G Sheehan, and
M J Newton, and
E P Frenkel
September 1982,
Horumon to rinsho. Clinical endocrinology,
R G Sheehan, and
M J Newton, and
E P Frenkel
March 1981,
Clinical chemistry,
