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The feasibility of determining the mass of both viable and infarcted myocardium from tomographic images of thallium-201 distribution in the heart was studied in two normal dogs and ten dogs with acute infarction. Twenty-four hours after occlusion, thallium-201 was injected and 10 min later the hearts were removed and transaxial emission computed tomograms were obtained. Using the computer, an operator defined the epi- and endocardial surfaces of the left ventricle and the area of infarction in each tomogram. The computer then calculated values for total left-ventricular mass (TLVM) infarcted mass (IM) and the percentage of the left ventricle infarcted (% LVI). The calculated values were compared with measured weights, and good correlation was found between them: for TLVM, r = 0.87; for IM, r = 0.90; and for %LVI, r = 0.87. Good interobserver and intra-observer correlations were also found. Thallium-201 emission computed tomography offers a potential means to measure both myocardial mass and acute myocardial injury.
J W Keyes, and
T J Brady, and
P F Leonard, and
D B Svetkoff, and
S M Winter, and
W L Rogers, and
E A Rose
April 1991,
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
J W Keyes, and
T J Brady, and
P F Leonard, and
D B Svetkoff, and
S M Winter, and
W L Rogers, and
E A Rose
November 1992,
The American journal of cardiology,
J W Keyes, and
T J Brady, and
P F Leonard, and
D B Svetkoff, and
S M Winter, and
W L Rogers, and
E A Rose
November 1991,
Annals of nuclear medicine,
J W Keyes, and
T J Brady, and
P F Leonard, and
D B Svetkoff, and
S M Winter, and
W L Rogers, and
E A Rose
February 1993,
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J W Keyes, and
T J Brady, and
P F Leonard, and
D B Svetkoff, and
S M Winter, and
W L Rogers, and
E A Rose
August 1987,
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
J W Keyes, and
T J Brady, and
P F Leonard, and
D B Svetkoff, and
S M Winter, and
W L Rogers, and
E A Rose
January 1977,
Heart & lung : the journal of critical care,
J W Keyes, and
T J Brady, and
P F Leonard, and
D B Svetkoff, and
S M Winter, and
W L Rogers, and
E A Rose
May 1982,
ZFA. Zeitschrift fur Allgemeinmedizin,
J W Keyes, and
T J Brady, and
P F Leonard, and
D B Svetkoff, and
S M Winter, and
W L Rogers, and
E A Rose
January 1985,
American heart journal,
J W Keyes, and
T J Brady, and
P F Leonard, and
D B Svetkoff, and
S M Winter, and
W L Rogers, and
E A Rose
April 1982,
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J W Keyes, and
T J Brady, and
P F Leonard, and
D B Svetkoff, and
S M Winter, and
W L Rogers, and
E A Rose
April 1990,
Meditsinskaia radiologiia,
