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E-rosette and surface Ig tests were used to study circulating T and B lymphocytes in 65 patients with chronic active liver disease (CALD), 15 healthy HBsAg carriers and 30 healthy controls. No significant variation in B lymphocytes was observed in CALD and in healthy HBsAg carriers. On the other hand, the absolute number and the percentage of T lymphocytes were significantly decreased in CALD, especially in cases negative for HBV infection markers.
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