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We conducted a prospective, randomized study to evaluate the influence of oral anticoagulation on graft patency early after aortocoronary bypass surgery. Eighty-nine patients who received 251 distal venous anastomoses were treated with phenoprocoumon, a vitamin K antagonist, starting on the seventh postoperative day; 84 patients with 238 distal venous anastomoses received no anticoagulation. Both groups were comparable with respect to age, exercise hemodynamics, extent of coronary disease and left ventricular dysfunction. In each group, 2.8 distal anastomoses were constructed per patient. Graft patency after surgery was 90.4% in the treatment group and 84.6% in the control group (p less than 0.015). All anastomoses were patent in 81% and 67% of patients, respectively (p less than 0.02). Flow measurements in 279 grafts suggest that grafts with a flow of less than 90 ml/min benefit from oral anticoagulation. No graft with a flow of more than 90 ml/min was occluded.
H Gohlke, and
C Gohlke-Bärwolf, and
P Stürzenhofecker, and
L Görnandt, and
B Ritter, and
M Reichelt, and
R Buchwalsky, and
M Schmuziger, and
H Roskamm
October 1983,
[Zasshi] [Journal]. Nihon Kyobu Geka Gakkai,
H Gohlke, and
C Gohlke-Bärwolf, and
P Stürzenhofecker, and
L Görnandt, and
B Ritter, and
M Reichelt, and
R Buchwalsky, and
M Schmuziger, and
H Roskamm
October 2010,
European heart journal,
H Gohlke, and
C Gohlke-Bärwolf, and
P Stürzenhofecker, and
L Görnandt, and
B Ritter, and
M Reichelt, and
R Buchwalsky, and
M Schmuziger, and
H Roskamm
July 1985,
Circulation,
H Gohlke, and
C Gohlke-Bärwolf, and
P Stürzenhofecker, and
L Görnandt, and
B Ritter, and
M Reichelt, and
R Buchwalsky, and
M Schmuziger, and
H Roskamm
December 1983,
Kyobu geka. The Japanese journal of thoracic surgery,
H Gohlke, and
C Gohlke-Bärwolf, and
P Stürzenhofecker, and
L Görnandt, and
B Ritter, and
M Reichelt, and
R Buchwalsky, and
M Schmuziger, and
H Roskamm
July 1984,
Kyobu geka. The Japanese journal of thoracic surgery,
H Gohlke, and
C Gohlke-Bärwolf, and
P Stürzenhofecker, and
L Görnandt, and
B Ritter, and
M Reichelt, and
R Buchwalsky, and
M Schmuziger, and
H Roskamm
January 1993,
Journal of cardiology,
H Gohlke, and
C Gohlke-Bärwolf, and
P Stürzenhofecker, and
L Görnandt, and
B Ritter, and
M Reichelt, and
R Buchwalsky, and
M Schmuziger, and
H Roskamm
June 1975,
Deutsche medizinische Wochenschrift (1946),
H Gohlke, and
C Gohlke-Bärwolf, and
P Stürzenhofecker, and
L Görnandt, and
B Ritter, and
M Reichelt, and
R Buchwalsky, and
M Schmuziger, and
H Roskamm
September 1986,
Journal of the American College of Cardiology,
H Gohlke, and
C Gohlke-Bärwolf, and
P Stürzenhofecker, and
L Görnandt, and
B Ritter, and
M Reichelt, and
R Buchwalsky, and
M Schmuziger, and
H Roskamm
November 1985,
Schweizerische medizinische Wochenschrift,
H Gohlke, and
C Gohlke-Bärwolf, and
P Stürzenhofecker, and
L Görnandt, and
B Ritter, and
M Reichelt, and
R Buchwalsky, and
M Schmuziger, and
H Roskamm
September 1986,
The Annals of thoracic surgery,
