Biomaterial Database

[Juvenile metrorrhagia by Willebrand Jürgens syndrome (author's transl)]. 1981

F Fischl, and W Grünberger

Juvenile bleeding is a symptom frequently observed in a children's gynecologic outpatient clinic. In rare cases this symptom does not represent a disturbance of hormonal regulation systems, but may be due to a coagulopathy. We represent a patient of an age of 12 years, who was admitted with the diagnosis: juvenile metrorrhagia. The final diagnosis: Willebrand-Jürgens syndrome would be established after invasive examinations and a series of blood tests. The presentation of this case suggests to consider coagulopathies as a cause of bleeding in similar cases. The special condition should be tested in cooperation with hematologists.

UI	MeSH Term	Description	Entries
D008796	Metrorrhagia	Abnormal uterine bleeding that is not related to MENSTRUATION, usually in females without regular MENSTRUAL CYCLE. The irregular and unpredictable bleeding usually comes from a dysfunctional ENDOMETRIUM.	Bleeding Between Periods,Breakthrough Bleeding,Dysfunctional Uterine Bleeding,Intermenstrual Bleeding,Spotting,Bleeding, Breakthrough,Dysfunctional Uterine Bleedings,Uterine Bleeding, Dysfunctional
D001779	Blood Coagulation Factors	Endogenous substances, usually proteins, that are involved in the blood coagulation process.	Clotting Factor,Coagulation Factors,Blood Coagulation Factor,Clotting Factors,Coagulation Factor,Coagulation Factor, Blood,Coagulation Factors, Blood,Factor, Coagulation,Factors, Coagulation,Factor, Blood Coagulation,Factor, Clotting,Factors, Blood Coagulation,Factors, Clotting
D001780	Blood Coagulation Tests	Laboratory tests for evaluating the individual's clotting mechanism.	Coagulation Tests, Blood,Tests, Blood Coagulation,Blood Coagulation Test,Coagulation Test, Blood,Test, Blood Coagulation
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014842	von Willebrand Diseases	Group of hemorrhagic disorders in which the VON WILLEBRAND FACTOR is either quantitatively or qualitatively abnormal. They are usually inherited as an autosomal dominant trait though rare kindreds are autosomal recessive. Symptoms vary depending on severity and disease type but may include prolonged bleeding time, deficiency of factor VIII, and impaired platelet adhesion.	Angiohemophilia,Hemophilia, Vascular,von Willebrand Disease,Vascular Pseudohemophilia,Von Willebrand Disorder,Von Willebrand's Factor Deficiency,von Willebrand Disease, Recessive Form,von Willebrand's Disease,von Willebrand's Diseases,Angiohemophilias,Disorder, Von Willebrand,Pseudohemophilia, Vascular,Pseudohemophilias, Vascular,Vascular Hemophilia,Vascular Hemophilias,Vascular Pseudohemophilias