Biomaterial Database

[Primary trigeminal projection to the brain stem-reticular formation. Experimental study in the rat]. 1981

R Insausti, and L M Gonzalo Sanz

By means of a transauricular approach, the trigeminal ganglion of the rat was lesioned in order to study the presence and distribution of the primary trigeminal afferents to the brain stem reticular formation. We could observe such projections to the reticular formation close to the trigeminal nuclei (lateral part of the n. reticularis ventralis and dorsalis, n. reticularis parvocellularis, reticular zone between the trigeminal n. principalis and the n. motorius trigemini) and also to the reticular formation more medially situated (medial part of the n. reticularis dorsalis and ventralis, n. reticularis gigantocellularis and n. reticularis pontis caudalis). Topographically, those projections correlated fair well with the extent of the trigeminal nuclei more related with sensorial transmission (n. principalis and subnuclei oralis and caudalis), specially the most medial of them. Moreover, although in a very much lesser intensity, we could see projections on the nuclei pallidus and magnus of the raphe system, and on the caudodorsal part of the central grey matter. The possible modulatory actions on the sensorial transmission and motor coordination of those projections are discussed.

UI	MeSH Term	Description	Entries
D012154	Reticular Formation	A region extending from the PONS & MEDULLA OBLONGATA through the MESENCEPHALON, characterized by a diversity of neurons of various sizes and shapes, arranged in different aggregations and enmeshed in a complicated fiber network.	Formation, Reticular,Formations, Reticular,Reticular Formations
D001933	Brain Stem	The part of the brain that connects the CEREBRAL HEMISPHERES with the SPINAL CORD. It consists of the MESENCEPHALON; PONS; and MEDULLA OBLONGATA.	Brainstem,Truncus Cerebri,Brain Stems,Brainstems,Cerebri, Truncus,Cerebrus, Truncus,Truncus Cerebrus
D000344	Afferent Pathways	Nerve structures through which impulses are conducted from a peripheral part toward a nerve center.	Afferent Pathway,Pathway, Afferent,Pathways, Afferent
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D012668	Trigeminal Ganglion	The semilunar-shaped ganglion containing the cells of origin of most of the sensory fibers of the trigeminal nerve. It is situated within the dural cleft on the cerebral surface of the petrous portion of the temporal bone and gives off the ophthalmic, maxillary, and part of the mandibular nerves.	Gasserian Ganglion,Semilunar Ganglion,Gasser's Ganglion,Trigeminal Ganglia,Ganglia, Trigeminal,Ganglion, Gasser's,Ganglion, Gasserian,Ganglion, Semilunar,Ganglion, Trigeminal,Gasser Ganglion,Gassers Ganglion,Semilunar Ganglions,Trigeminal Ganglias,Trigeminal Ganglions
D014276	Trigeminal Nerve	The 5th and largest cranial nerve. The trigeminal nerve is a mixed motor and sensory nerve. The larger sensory part forms the ophthalmic, mandibular, and maxillary nerves which carry afferents sensitive to external or internal stimuli from the skin, muscles, and joints of the face and mouth and from the teeth. Most of these fibers originate from cells of the TRIGEMINAL GANGLION and project to the TRIGEMINAL NUCLEUS of the brain stem. The smaller motor part arises from the brain stem trigeminal motor nucleus and innervates the muscles of mastication.	Cranial Nerve V,Fifth Cranial Nerve,Nerve V,Nervus Trigeminus,Cranial Nerve, Fifth,Fifth Cranial Nerves,Nerve V, Cranial,Nerve Vs,Nerve, Fifth Cranial,Nerve, Trigeminal,Trigeminal Nerves,Trigeminus, Nervus
D014278	Trigeminal Nuclei	Nuclei of the trigeminal nerve situated in the brain stem. They include the nucleus of the spinal trigeminal tract (TRIGEMINAL NUCLEUS, SPINAL), the principal sensory nucleus, the mesencephalic nucleus, and the motor nucleus.	Trigeminal Nuclear Complex,Nuclear Complex, Trigeminal,Nuclear Complices, Trigeminal,Nuclei, Trigeminal,Nucleus, Trigeminal,Trigeminal Nuclear Complices,Trigeminal Nucleus
D051381	Rats	The common name for the genus Rattus.	Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus