Aortocoronary bypass grafting: an internist's perspective. 1982

H D McIntosh

Seven hundred fifty thousand to 1 million persons in this country have undergone aortocoronary bypass grafting since 1968, but many questions regarding the indications for the procedure and its advantages and disadvantages persist. Based on this surgical experience and on observations made during the last decade regarding nonoperative therapy and changes in the natural history of coronary heart disease, at least eight considerations should influence attitudes regarding the role of surgery: (1) The operation is a significant addition to the management of some patients with coronary heart disease. (2) The operative mortality in many centers is gratifyingly low. (3) Mortality from coronary heart disease in this country has declined strikingly during the past decade. (4) Because of the declining mortality from coronary heart disease, the prognosis of patients with the disease seen in 1980 is uncertain. (5) Coronary heart disease is a progressive disease and surgery does not prevent the progression of the disease in the native circulation. (6) Reports of therapeutic results, whether surgical or medical, are often biased toward the positive side. (7) Aortocoronary bypass does appear to postpone premature death in symptomatic patients with stenosis of the left main coronary artery, and possibly in symptomatic patients with three-vessel disease and modest impairment of left ventricular contractility. (8) Conclusions of meetings of "experts" regarding therapy may not by applicable to the country at large. The profession and the general public should be so informed.

UI MeSH Term Description Entries
D010686 Philosophy, Medical The underlying rationale or theoretical basis for the principles of MEDICINE. Medical Philosophy
D011379 Prognosis A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations. Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D003327 Coronary Disease An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels. Coronary Heart Disease,Coronary Diseases,Coronary Heart Diseases,Disease, Coronary,Disease, Coronary Heart,Diseases, Coronary,Diseases, Coronary Heart,Heart Disease, Coronary,Heart Diseases, Coronary
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001026 Coronary Artery Bypass Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion. Aortocoronary Bypass,Bypass, Coronary Artery,Bypass Surgery, Coronary Artery,Coronary Artery Bypass Grafting,Coronary Artery Bypass Surgery,Aortocoronary Bypasses,Artery Bypass, Coronary,Artery Bypasses, Coronary,Bypass, Aortocoronary,Bypasses, Aortocoronary,Bypasses, Coronary Artery,Coronary Artery Bypasses
D013673 Technology Assessment, Biomedical Evaluation of biomedical technology in relation to cost, efficacy, utilization, etc., and its future impact on social, ethical, and legal systems. Assessment, Biomedical Technology,Assessment, Technology,Biomedical Technology Assessment,Technology Assessment,Technology Assessment, Health,Assessment, Health Technology,Assessments, Biomedical Technology,Assessments, Health Technology,Assessments, Technology,Biomedical Technology Assessments,Health Technology Assessment,Health Technology Assessments,Technology Assessments,Technology Assessments, Biomedical,Technology Assessments, Health

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