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Cell-mediated immune responses were examined during the menstrual cycle of 10 healthy females and in 90 pregnant females, 10 for each month of gestation, and in 10 females 2--4 weeks after normal delivery. Lymphocytes and their subpopulations and PPD hypersensitivity skin tests were investigated. The lymphocyte subpopulation T-cells showed statistically significant depression at the time of ovulation (P less than 0.01) and during the entire period of gestation (P less than 0.001) with recovery in the post-partum period. There was borderline PPD skin response during pregnancy which became positive after parturition. These changes were demonstrated to be specific to conception but the exact mechanism of the T-cell depression is not known. There was a corresponding rise in the B-cell count.
S Agarwal, and
H S Shukla, and
M Verma, and
S C Gupta, and
K Mukherjee
September 1983,
American journal of reproductive immunology : AJRI : official journal of the American Society for the Immunology of Reproduction and the International Coordination Committee for Immunology of Reproduction,
S Agarwal, and
H S Shukla, and
M Verma, and
S C Gupta, and
K Mukherjee
November 1950,
Le Scalpel,
S Agarwal, and
H S Shukla, and
M Verma, and
S C Gupta, and
K Mukherjee
May 1979,
Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology,
S Agarwal, and
H S Shukla, and
M Verma, and
S C Gupta, and
K Mukherjee
December 2022,
American journal of reproductive immunology (New York, N.Y. : 1989),
S Agarwal, and
H S Shukla, and
M Verma, and
S C Gupta, and
K Mukherjee
January 1955,
Medecine tropicale : revue du Corps de sante colonial,
S Agarwal, and
H S Shukla, and
M Verma, and
S C Gupta, and
K Mukherjee
January 1990,
European journal of obstetrics, gynecology, and reproductive biology,
S Agarwal, and
H S Shukla, and
M Verma, and
S C Gupta, and
K Mukherjee
May 1958,
Klinische Wochenschrift,
S Agarwal, and
H S Shukla, and
M Verma, and
S C Gupta, and
K Mukherjee
November 1982,
Transplantation,
S Agarwal, and
H S Shukla, and
M Verma, and
S C Gupta, and
K Mukherjee
January 1985,
Annals of clinical and laboratory science,
S Agarwal, and
H S Shukla, and
M Verma, and
S C Gupta, and
K Mukherjee
January 1979,
Thrombosis research,
