Biomaterial Database

[Sarcomere supercontraction during Zenker's necrosis of skeletal muscle fibers]. 1982

S A Krolenko, and Iu S Borovikov, and V P Kirillina, and N A Rizhamadze

The ultrastructure and localization of supercontracted sarcomeres during the spreading (Zenker's) necrosis of twitch and tonic frog fibres and the fast- and slow-twitch rat fibres are described. The formation of supercontracted sarcomeres proceeds mainly by the sliding mechanism. Contracted bands are characterized by homogenization of myosin and actin filaments and by the disappearance of Z-band structures. In the calcium-free medium some myosin filaments pass through the whole depth of the contracted band or are seen bending and deviating backwards upon approaching the contracted band. In calcium-free solution supercontracted sarcomeres often form narrow strips (2-5 sarcomere long), crossing the fibres. The transverse elignment of sarcomeres is typical of supercontracted portion of fibres.

UI	MeSH Term	Description	Entries
D009119	Muscle Contraction	A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.	Inotropism,Muscular Contraction,Contraction, Muscle,Contraction, Muscular,Contractions, Muscle,Contractions, Muscular,Inotropisms,Muscle Contractions,Muscular Contractions
D009132	Muscles	Contractile tissue that produces movement in animals.	Muscle Tissue,Muscle,Muscle Tissues,Tissue, Muscle,Tissues, Muscle
D009210	Myofibrils	The long cylindrical contractile organelles of STRIATED MUSCLE cells composed of ACTIN FILAMENTS; MYOSIN filaments; and other proteins organized in arrays of repeating units called SARCOMERES .	Myofilaments,Myofibril,Myofilament
D009336	Necrosis	The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
D011896	Rana temporaria	A species of the family Ranidae occurring in a wide variety of habitats from within the Arctic Circle to South Africa, Australia, etc.	European Common Frog,Frog, Common European,Common European Frog,Common Frog, European,European Frog, Common,Frog, European Common
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D051381	Rats	The common name for the genus Rattus.	Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus
D066298	In Vitro Techniques	Methods to study reactions or processes taking place in an artificial environment outside the living organism.	In Vitro Test,In Vitro Testing,In Vitro Tests,In Vitro as Topic,In Vitro,In Vitro Technique,In Vitro Testings,Technique, In Vitro,Techniques, In Vitro,Test, In Vitro,Testing, In Vitro,Testings, In Vitro,Tests, In Vitro,Vitro Testing, In