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The cardiovascular effects of thiopentone 3 mg kg-1 and midazolam 0.3 mg kg-1 were observed during induction of anaesthesia in 16 premedicated patients about to undergo myocardial revascularization. There were no significant changes in either group in cardiac output or central venous pressure. The heart rate in both groups showed an increase at 3 min and thereafter returned to control values. After 3 min, there was a significant decrease in both arterial pressure and peripheral resistance by 12% and 15% (mean values) respectively from control values in the group receiving midazolam, whereas after thiopentone the peripheral resistance increased by approximately 13% and was not affected by a further dose of thiopentone 1 mg kg-1.
D Al-Khudhairi, and
J G Whitwam, and
M K Chakrabarti, and
H Askitopoulou, and
E M Grundy, and
S Powrie
August 1985,
Anaesthesia,
D Al-Khudhairi, and
J G Whitwam, and
M K Chakrabarti, and
H Askitopoulou, and
E M Grundy, and
S Powrie
January 1983,
Canadian Anaesthetists' Society journal,
D Al-Khudhairi, and
J G Whitwam, and
M K Chakrabarti, and
H Askitopoulou, and
E M Grundy, and
S Powrie
December 1981,
Acta anaesthesiologica Scandinavica,
D Al-Khudhairi, and
J G Whitwam, and
M K Chakrabarti, and
H Askitopoulou, and
E M Grundy, and
S Powrie
April 1988,
Acta anaesthesiologica Scandinavica,
D Al-Khudhairi, and
J G Whitwam, and
M K Chakrabarti, and
H Askitopoulou, and
E M Grundy, and
S Powrie
November 1985,
Canadian Anaesthetists' Society journal,
D Al-Khudhairi, and
J G Whitwam, and
M K Chakrabarti, and
H Askitopoulou, and
E M Grundy, and
S Powrie
November 2003,
JPMA. The Journal of the Pakistan Medical Association,
D Al-Khudhairi, and
J G Whitwam, and
M K Chakrabarti, and
H Askitopoulou, and
E M Grundy, and
S Powrie
July 1980,
Canadian Anaesthetists' Society journal,
D Al-Khudhairi, and
J G Whitwam, and
M K Chakrabarti, and
H Askitopoulou, and
E M Grundy, and
S Powrie
July 2001,
Medical journal, Armed Forces India,
D Al-Khudhairi, and
J G Whitwam, and
M K Chakrabarti, and
H Askitopoulou, and
E M Grundy, and
S Powrie
May 1982,
Canadian Anaesthetists' Society journal,
D Al-Khudhairi, and
J G Whitwam, and
M K Chakrabarti, and
H Askitopoulou, and
E M Grundy, and
S Powrie
March 1988,
Anaesthesia,
